Author

Marilena Christoforou

Imperial College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

Abdelmadjid Atrih· 1 shared Abigail Gaffar· 1 shared Andreas MargrafiD· 1 shared Audrey M. MicheliD· 1 shared Axel Bellotti· 1 shared Ayda Henriques SchneideriD· 1 shared Chiara CecconelloiD· 1 shared Dianne CooperiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Abdelmadjid Atrih

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2 papers

Recent·Most cited

An integrated stress response-independent role of GCN2 prevents excessive ribosome biogenesis and mRNA translation

Mónica Román-Trufero, Istvan T. Kleijn, Kevin Blighe, Jinglin Zhou, Paula Saavedra-García, Abigail Gaffar, Marilena Christoforou, Axel Bellotti, Joel M. Abrahams, Abdelmadjid Atrih, Douglas J. Lamont, Marek Gierliński, Pooja Jayaprakash, Audrey M. Michel, Eric Ofori Aboagye, , Holger W. Auner

This study identifies an ISR-independent role of GCN2 in preventing excessive ribosome biogenesis and mRNA translation, with implications for cancer therapy.

Life Science Alliance · Mar 3, 2025Peer-reviewedCancer Biology

Formyl-peptide receptor type 2 activation mitigates secondary organ damage in inflammatory arthritis

Andreas Margraf, Jianmin Chen, Marilena Christoforou, Pol Claria-Ribas, Ayda Henriques Schneider, Chiara Cecconello, Wei Bu, Paul R. C. Imbert, Thomas D Wright, Stefan Russo, Isobel Alice Blacksell, Duco Steven Koenis, Jesmond Dalli, John A. Lupisella, Nicholas R. Wurtz, , Mauro Perretti

This study shows that activating FPR2 with a small molecule agonist reduces cardiac and lung damage in arthritic mice by decreasing inflammation and fibrosis.

bioRxiv · Feb 3, 2025 · PreprintPharmacology & Toxicology