Microbial metabolism of mannitol as a tracer for the non-invasive measurement of oral-cecal transit
Daniel E. Vieira, Emily M. Langmeyer, Marissa D. Cortopassi, William Bernard Rubio, Sarah N. Flier, Lynn Bry, Alexander S. Banks
This paper introduces a non-invasive method to measure oral-cecal transit time in mice by tracking microbial oxidation of 13C-mannitol to 13CO2 using spectroscopy and calorimetry.
American Journal of Physiology-Endocrinology and Metabolism · Aug 20, 2026Peer-reviewedPhysiology