Author

Mark A. Durham

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Huda Yahya ZoghbiiD· 3 shared Zhandong LiuiD· 3 shared Alexander J. TrostleiD· 2 shared Ying‐Wooi WaniD· 2 shared Ashley G. AndersoniD· 1 shared Binoy ShivannaiD· 1 shared Chongyuan LuoiD· 1 shared E.H.Y. ChuiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Huda Yahya ZoghbiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Functional divergence of Capicua isoforms explains differential tissue vulnerability in neurological disease

Hamin Lee, Esmeralda Villavicencio Gonzalez, Elias M. Rivera, Mark A. Durham, Ronald Richman, E.H.Y. Chu, Kailey Xia, Hu Chen, Zhandong Liu, Surabi Veeraragavan, Binoy Shivanna, Huda Yahya Zoghbi

The paper shows that different isoforms of CIC interact with paralogs ATXN1 and ATXN1L, leading to distinct phenotypes and explaining tissue-specific vulnerability in neurological diseases.

Genes & Development · Jul 20, 2026Peer-reviewedMolecular Biology

MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function

Sameer S. Bajikar, Ashley G. Anderson, Jian Zhou, Mark A. Durham, Alexander J. Trostle, Ying‐Wooi Wan, Zhandong Liu, Huda Yahya Zoghbi

This study identifies Gdf11 as a MeCP2-regulated gene critical for neurological function, showing that altering its dosage affects behavior and longevity in mouse models.

eLife · Feb 10, 2023Peer-reviewedNeuroscience

Loss of Dnmt3a dependent methylation in inhibitory neurons impairs neural function through a mechanism that impacts Rett syndrome

Laura A. Lavery, Kerstin Ure, Ying‐Wooi Wan, Chongyuan Luo, Alexander J. Trostle, Wei Wang, Haijing Jin, Joanna Lopez, Jacinta D. Lucero, Mark A. Durham, Rosa Castanon, Joseph R. Nery, Zhandong Liu, Margaret A. Goodell, Joseph R. Ecker, , Huda Yahya Zoghbi

This study shows that loss of Dnmt3a or MeCP2 in inhibitory neurons leads to distinct but overlapping neurological and molecular effects, with mCH playing a key role in Rett Syndrome pathogenesis.

eLife · Mar 11, 2020Peer-reviewedNeuroscience