Author

Mark C. Lin

Emory National Primate Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:rat· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:host-pathogen & immune response· 1 Assay:long-read sequencing· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Amit A. UpadhyayiD· 2 shared Kirti A. KarunakaraniD· 2 shared Stacey A. LappiD· 2 shared Steven E. BosingeriD· 2 shared Thang Ton· 2 shared Adam J. EricseniD· 1 shared Amanda MetziD· 1 shared Amelia Wilkes· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersImmunology

Amit A. UpadhyayORCID

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2 papers

Recent·Most cited

Passive infusion of an S2-Stem broadly neutralizing antibody protects against SARS-CoV-2 infection and lower airway inflammation in rhesus macaques

Steven E. Bosinger, Christopher T Edwards, Kirti A. Karunakaran, Elijah Garcia, Nathan Beutler, Matthew Gagné, Nadia Golden, Hadj Aoued, Kathryn Pellegrini, Matthew R. Burnett, Christopher Cole Honeycutt, Stacey A. Lapp, Thang Ton, Mark C. Lin, Metz Amanda, , Dennis R. Burton

This study shows that the S2-targeting antibody CC40.8 reduces SARS-CoV-2 viral loads and lower airway inflammation in rhesus macaques, supporting its potential as a broad coronavirus vaccine strategy.

PLoS Pathogens · Jan 23, 2025Peer-reviewedImmunology

A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques

Ayelet Peres, Amit A. Upadhyay, Vered Klein, Swati Saha, Oscar L. Rodriguez, Zachary Matthew Vanwinkle, Kirti A. Karunakaran, Amanda Metz, William Lauer, Mark C. Lin, Timothy Melton, Lukas Granholm, Pazit Polak, Samuel M Peterson, Eric J Peterson, , Steven E. Bosinger

The paper develops methodologies to generate and analyze immunoglobulin loci variation in rhesus macaques, revealing extensive diversity and expanding existing allele sets by 60%.

bioRxiv · Jan 7, 2025 · PreprintImmunology