Author

William Lauer

University of Louisville

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Assay:DNA methylation· 2 Assay:long-read sequencing· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Melissa Laird SmithiD· 4 shared Corey T. WatsoniD· 2 shared Kaitlyn M. Shields· 2 shared Aaron A.R. TobianiD· 1 shared Adam J. EricseniD· 1 shared Adonis A. RubioiD· 1 shared Alan EngelmaniD· 1 shared Ali DaneshiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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4 shared papersGenomics

Melissa Laird SmithORCID

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Author profile →

4 papers

Recent·Most cited

DNA 6mA marks transcriptionally active chromatin in malaria parasites

Dhanasekaran Seshan, William Lauer, Gautam Sarkar, Mohan Govindasamy, Connor S. Murray, Eric Lieberman Greer, Melissa Laird Smith, Shruthi Sridhar Vembar

The paper identifies 6mA methylation in Plasmodium falciparum, showing it is associated with active chromatin and transcription, and identifies a methyltransferase involved in this modification.

BMC Microbiology · Oct 9, 2026Peer-reviewedGenomics

Disruption of a CCR5-like immunoglobulin gene is linked to plague susceptibility in black-footed ferrets

Yana Safonova, Taylor A. Pursell, Caleb S. Whitley, Katelyn R. Sheneman, Anna Mikhailova, Vinamratha Pattar, Mariia Pospelova, Adonis A. Rubio, Katalin Voss, Jordan M. Welker, Anton Zamyatin, Anton Bankevich, Jef D. Boeke, Emily Haraguchi, Elizabeth Hudson, , Klaus‐Peter Koepfli

The paper identifies a disrupted CCR5-like immunoglobulin gene in black-footed ferrets linked to increased susceptibility to plague caused by Yersinia pestis.

bioRxiv · Jul 10, 2026 · PreprintImmunology

Development and validation of HIV SMRTcap for the characterization of HIV-1 reservoirs across tissues and subtypes

Ghazal Sadri, Steven T. Nadakal, William Lauer, Justin T. Kos, Parmit Kumar Singh, Erin Elliott, Catherine W. Kaiser, Easton E. Ford, Nadia Richardson, Kaitlyn M. Shields, Elizabeth Hudson, Noemi Linden, Ali Danesh, James Powell, Peter E. Warburton, , Melissa Laird Smith

The paper introduces HIV SMRTcap, a method for characterizing HIV-1 reservoirs by identifying integration sites and proviral integrity using long-read sequencing, and validates its performance across subtypes and tissue samples.

PLoS Pathogens · Jan 13, 2026Peer-reviewedGenomics

A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques

Ayelet Peres, Amit A. Upadhyay, Vered Klein, Swati Saha, Oscar L. Rodriguez, Zachary Matthew Vanwinkle, Kirti A. Karunakaran, Amanda Metz, William Lauer, Mark C. Lin, Timothy Melton, Lukas Granholm, Pazit Polak, Samuel M Peterson, Eric J Peterson, , Steven E. Bosinger

The paper develops methodologies to generate and analyze immunoglobulin loci variation in rhesus macaques, revealing extensive diversity and expanding existing allele sets by 60%.

bioRxiv · Jan 7, 2025 · PreprintImmunology