Author

Michael Keegan

King's College London

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

Alessia GentiliiD· 1 shared Cecilia ZazaiD· 1 shared David J. WilliamsoniD· 1 shared Harry HolmesiD· 1 shared Irene Carlón-AndrésiD· 1 shared James L. DalyiD· 1 shared Joseph W. ThrushiD· 1 shared Katie J. DooresiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiophysics

Alessia GentiliORCID

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1 paper

Recent·Most cited

Gag proteolysis drives HIV-1 envelope conformational closure through the gp41 cytoplasmic tail

David J. Williamson, Cecilia Zaza, Irene Carlón-Andrés, Harry Holmes, Alessia Gentili, Joseph W. Thrush, James L. Daly, Michael Keegan, Katie J. Doores, Tomas Malinauskas, Stuart J. D. Neil, Michael H. Malim, Sabrina Simoncelli, Sergi Padilla‐Parra

This study shows that Gag proteolysis drives HIV-1 Env conformational closure through the gp41 cytoplasmic tail, revealing a mechanism for immune evasion.

bioRxiv · Oct 4, 2026 · PreprintBiophysics