Author

Michelle L. Thaxton

University of California, Los Angeles

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Alexander J. RitteriD· 2 shared Dinesh S. RaoiD· 2 shared Georgia SchereriD· 2 shared Gunjan SharmaiD· 2 shared Jacob P. SorrentinoiD· 2 shared Jeremy R. SanfordiD· 2 shared Neil K. GargiD· 2 shared Robert D. DamoiseauxiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Alexander J. RitterORCID

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2 papers

Recent·Most cited

A small molecule inhibitor of RNA-binding protein IGF2BP3 shows anti-leukemic activity

Amit K Jaiswal, Georgia Scherer, Michelle L. Thaxton, Jacob P. Sorrentino, Constance Yuen, Milauni M. Mehta, Gunjan Sharma, Tasha Lotus Lin, Tiffany M. Tran, Amanda Cohen, Alexander J. Ritter, Rishi Sury Kotecha, Jeremy R. Sanford, Robert D. Damoiseaux, Neil K. Garg, Dinesh S. Rao

This paper identifies I3IN-002, a small molecule inhibitor of IGF2BP3, which shows anti-leukemic activity in cell lines and a mouse model.

Haematologica · Nov 27, 2025Peer-reviewedCancer Biology

Metabolic regulation of RNA methylation by the m6A-reader IGF2BP3

Gunjan Sharma, Martin E Gutierrez, Anthony E. Jones, S. S. Kapoor, Amit Kumar Jaiswal, Zachary T. Neeb, Amy Rios, Poornima Dorairaj, Michelle L. Thaxton, Tasha Lotus Lin, Tiffany M. Tran, Lyna E.S. Kabbani, Alexander J. Ritter, Georgia Scherer, Jacob P. Sorrentino, , Dinesh S. Rao

This study shows IGF2BP3 regulates RNA methylation by altering cellular metabolism to increase SAM production, enhancing m6A modifications and gene expression in leukemia.

Cell Reports · Sep 27, 2025Peer-reviewedCancer Biology