Author

Miles W Carroll

Centre for Human Genetics

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:phylogenetics / evolution· 2 Organism:virus· 2 Approach:comparative / phylogenetic analysis· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Raymond J. OwensiD· 2 shared A Sarah Walker· 1 shared Abayomi S Olabode· 1 shared Adam KirbyiD· 1 shared Alison VaughaniD· 1 shared Andrew OweniD· 1 shared Anja KipariD· 1 shared Daniele F. MegaiD· 1 shared

Activity by Year

2016-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

Raymond J. OwensORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The pharmacokinetics, bio-distribution and therapeutic efficacy of a trimeric nanobody against SARS-CoV-2 in the golden Syrian hamster COVID-19 model

Parul Sharma, Daniele F. Mega, Adam Kirby, Imogen Buckle, Anja Kipar, Jordan J. Clark, Eleanor G. Bentley, Lauren E.-A. Eyssen, Edyta Kijak, Joanne Herriott, Joanne Sharp, Andrew Owen, Miles W Carroll, Raymond J. Owens, James P. Stewart

This study evaluates the pharmacokinetics, biodistribution, and therapeutic efficacy of a trimeric nanobody against SARS-CoV-2 in golden Syrian hamsters, showing that intranasal administration provides effective respiratory exposure and therapeutic benefit.

bioRxiv · Oct 6, 2026 · PreprintMicrobiology

Structural analysis reveals high-order Nipah Virus Fusion Protein assemblies and interactions with neutralising nanobodies

Joseph W. Thrush, Luke M. Jones, Irene Carlón-Andrés, Miles W Carroll, Sergi Padilla‐Parra, Raymond J. Owens

The paper uses cryo-electron tomography to study NiV fusion protein assemblies and shows nanobodies block inter-trimer interactions, inhibiting viral entry.

bioRxiv · May 23, 2026 · PreprintMolecular Biology

Nanopore metagenomic sequencing of full length human metapneumovirus (HMPV) within a unique sub-lineage

Yifei Xu, Kuiama Lewandowski, Sheila Lumley, Nicholas D Sanderson, Alison Vaughan, Richard T Vipond, Miles W Carroll, Katie Jeffery, Dona Foster, A Sarah Walker, Timothy E. A. Peto, Derrick W Crook, Steven T Pullan, Philippa C. Matthews

This study uses Nanopore metagenomic sequencing to directly sequence the full-length HMPV genome from a UK patient, identifying a unique genetic group and demonstrating the utility of Nanopore for clinical diagnosis.

bioRxiv · Dec 17, 2018 · PreprintMicrobiology

Identification of important amino acid replacements in the 2013-2016 Ebola virus outbreak

Abayomi S Olabode, Derek Gatherer, Xiaowei Jiang, David Matthews, Julian A Hiscox, Stephan Gunther, Miles W Carroll, Simon C Lovell, David L Robertson

The paper analyzes amino acid replacements in the 2013-2016 Ebola virus outbreak, identifying one significant mutation that may affect host specificity and adaptation to humans.

bioRxiv · Sep 14, 2016 · PreprintMicrobiology