Author

Munir H. Buhaya

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Emina H. HuangiD· 3 shared Zhikai ChiiD· 3 shared Robert C. Fisher· 2 shared Adil R. KhaniD· 1 shared Afeefah Khazi-SyediD· 1 shared Andrew R. JamiesoniD· 1 shared Angela Fan· 1 shared Bo YaoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersBioinformatics

Emina H. HuangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Spatial Topology Reveals Biologically Distinct Recurrent Motifs in Colorectal Cancer

Jia Yao, Yuqiu Yang, Y Jiang, Qin Zhou, Ling Cai, Wenqi Shi, Zhikai Chi, Peiran Quan, Munir H. Buhaya, Bo Yao, Gu Xiao, Emina H. Huang, Y D Xie

The paper introduces STORM, a method to identify recurrent spatial motifs in colorectal cancer without cell-type labels, finding a fibroblast barrier linked to immune exclusion and prognosis.

bioRxiv · Jul 15, 2026 · PreprintBioinformatics

Inflammatory Stromal Aging in Ulcerative Colitis and Colitis-Associated Cancer

Khalil Almotah, Uyen Tran, Haylee Gilbert, Robert Allen Schweickart, Robert C. Fisher, Yaroslav Bisikalo, Manal Ali, Munir H. Buhaya, Mingyuan Cheng, Michael W. Cruise, Zhikai Chi, Samaneh Kamali Sarvestani, Emina H. Huang, Oliver Wessely

This study investigates how inflammatory fibroblasts in ulcerative colitis and colitis-associated cancer contribute to disease progression through senescence and epigenetic memory.

bioRxiv · May 20, 2026 · PreprintCancer Biology

Biomechanical Phenotyping Reveals Unique Mechanobiological Signatures of Early-Onset Colorectal Cancer

Nicole C. Huning, Munir H. Buhaya, Victor Nguyen, Afeefah Khazi-Syed, Haider Ali, Adil R. Khan, Angela Fan, Robert C. Fisher, Zhikai Chi, Indu Raman, Guangchun Chen, Chengsong Zhu, Mengxi Yu, Andrew R. Jamieson, Sara Roccabianca, , Jacopo Ferruzzi

This study identifies biomechanical stiffening and fibrotic remodeling as hallmarks of early-onset colorectal cancer, showing their role in tumor initiation.

Advanced Science · Dec 1, 2025Peer-reviewedBioengineering