Author

Myriam Shafie

Wellcome Sanger Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1 Research Focus:software / tool· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Adam James ReidiD· 1 shared Aidan Mark EmeryiD· 1 shared Alan TraceyiD· 1 shared Alexandra Peña Fernández· 1 shared Andrew R. LeachiD· 1 shared Andrzej DrozdzeckiiD· 1 shared Antonio MuroiD· 1 shared Antonio OsunaiD· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Adam James ReidORCID

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2 papers

Recent·Most cited

Systematic optimization of Cas12a base editors in wheat and maize using the ITER platform

Christophe Gaillochet, Alexandra Peña Fernández, Vera Goossens, Katelijn D’Halluin, Andrzej Drozdzecki, Myriam Shafie, Julie Van Duyse, Gert Van Isterdael, Camila Gonzalez, Mattias Vermeersch, Jonas De Saeger, Ward Develtere, Dominique Audenaert, David De Vleesschauwer, Frank Meulewaeter, Thomas B. Jacobs

The paper develops an optimized LbCas12a-ABE base editor in wheat and maize using the ITER platform, achieving 40% activity on a GFP reporter through iterative design.

bioRxiv · May 11, 2022 · PreprintSynthetic Biology

Comparative genomics of the major parasitic worms

Avril Coghlan, James Anthony Cotton, Nancy E. Holroyd, Adam James Reid, Diogo M. Ribeiro, Eleanor Stanley, Helen L. Beasley, Hayley M. Bennett, Stephen R. Doyle, Daria Gordon, Bhavana Harsha, Thomas Huckvale, Jane Lomax, Gabriel Rinaldi, Myriam Shafie, , Lian-Chen Wang

This paper compares genomes of 81 nematode and platyhelminth species to identify gene families related to parasitism and prioritize new drug targets.

Nature Genetics · Oct 29, 2018Peer-reviewedGenomics