Author

N. A. Feasey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Ecology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:whole-genome sequencing· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:variant calling· 3 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Organism:E. coli· 2

Frequent Co-Authors

A. P. Roberts· 3 shared J. M. Lewis· 3 shared M. A. Beale· 3 shared M. Mphasa· 3 shared A. T. Hubbard· 2 shared B. M. Perez-Sepulveda· 2 shared C. V. Pulford· 2 shared E. Heinz· 2 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. P. Roberts

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Molecular mechanisms of re-emerging chloramphenicol susceptibility in extended-spectrum beta-lactamase producing Enterobacterales

F. E. Graf, R. N. Goodman, S. Gallichan, S. Forrest, E. Picton-Barlow, A. J. Fraser, M.-D. Phan, M. Mphasa, A. T. Hubbard, P. Musicha, M. A. Schembri, A. P. Roberts, T. Edwards, J. M. Lewis, N. A. Feasey

The paper investigates the re-emerging chloramphenicol susceptibility in ESBL-producing Enterobacterales by analyzing genotype-phenotype discordance and molecular mechanisms.

bioRxiv · Nov 16, 2023Microbiology

Household geckos as a potential vector for Salmonella transmission in Malawi

C. N. Wilson, P. Musicha, M. A. Beale, Y. Diness, O. Kanjerwa, C. Salifu, Z. J. Katuah, P. Duncan, J. Nyangu, A. Mungu, M. Deleza, L. Banda, N. Elviss, C. Jewell, G. Pinchbeck, , E. M. Fevre

The paper isolates Salmonella from gecko stool samples in Malawi and shows they carry multiple serovars, suggesting a role in household transmission.

bioRxiv · Sep 8, 2023 · PreprintEcology

An accessible, efficient and global approach for the large-scale sequencing of bacterial genomes

B. M. Perez-Sepulveda, D. Heavens, C. V. Pulford, A. V. Predeus, R. Low, H. Webster, C. Schudoma, W. Rowe, J. Lipscombe, C. Watkins, B. Kumwenda, N. Shearer, K. Costigan, K. S. Baker, N. A. Feasey, , The 10KSG consortium

The paper describes a low-cost, efficient pipeline for large-scale bacterial genome sequencing, demonstrating its application in collecting and sequencing 10,419 isolates from multiple countries.

Genome Biology · Dec 21, 2021Peer-reviewedMicrobiology

Genomic and antigenic diversity of carried Klebsiella pneumoniae isolates mirrors that of invasive isolates in Blantyre, Malawi

J. M. Lewis, M. Mphasa, R. Banda, M. A. Beale, J. Mallewa, E. Heinz, N. R. Thomson, N. A. Feasey

This study compares genomic and antigenic diversity of colonizing and invasive Klebsiella pneumoniae isolates in Blantyre, Malawi, finding similar population structures and highlighting the potential of colonizing isolates for vaccine development.

bioRxiv · Oct 7, 2021Microbiology

Genomic analysis of extended-spectrum beta-lactamase (ESBL) producing Escherichia coli colonising adults in Blantyre, Malawi reveals previously undescribed diversity.

J. M. Lewis, M. Mphasa, R. Banda, M. A. Beale, J. Mallewa, C. Anscombe, A. Zuza, A. P. Roberts, E. Heinz, N. R. Thomson, N. A. Feasey

This study sequenced ESBL-producing E. coli from Malawi to assess genetic diversity and AMR determinants, revealing locally circulating subclades and carbapenemase genes.

bioRxiv · Oct 7, 2021Microbiology

Isolation and characterisation of bacteriophages with activity against invasive non-typhoidal Salmonella causing bloodstream infection in Malawi

E. V. Rodwell, N. Wenner, C. V. Pulford, Y. Cai, A. Bowers-Barnard, A. Beckett, J. Rigby, D. M. Picton, T. R. Blower, N. A. Feasey, J. C. D. Hinton, B. M. Perez-Sepulveda

This study isolates and characterizes bacteriophages active against invasive non-typhoidal Salmonella causing bloodstream infections in Malawi, identifying three phylogenetic clusters with varying host ranges.

bioRxiv · Feb 18, 2021Microbiology

Effect of environment on the evolutionary trajectories and growth characteristics of antibiotic- resistant Escherichia coli mutants

A. T. Hubbard, N. V. Jafari, N. A. Feasey, J. L. Rohn, A. P. Roberts

This study shows that growth media significantly affects the isolation and fitness of antibiotic-resistant E. coli mutants, highlighting the limitations of using single culture protocols for predicting in vivo bacterial behavior.

bioRxiv · Feb 28, 2019Microbiology