E. Heinz

Establishment and comparative genomics of a high-quality collection of mosquito-associated bacterial isolates -- MosAIC (Mosquito-Associated Isolate Collection)

The paper establishes a high-quality bacterial isolate collection (MosAIC) from mosquitoes, providing genomic data and phylogenomic analysis to study mosquito-associated bacteria.

Aedes aegypti gut transcriptomes respond differently to microbiome transplants from field-caught or laboratory-reared mosquitoes.

This study compares gut transcriptomic responses of mosquitoes to microbiome transplants from field-caught versus laboratory-reared donors, finding greater gene expression variation with field microbiomes.

Vertical and horizontal transmission of cell fusing agent virus in Aedes aegypti

This study investigates the transmission routes of CFAV in Aedes aegypti, finding vertical and paternal transmission rates and suggesting strategies for arbovirus control.

The phylogenomic landscape of the genus Serratia

This study analyzes 664 Serratia genomes to reveal population structure, ecological niche alignment, and gene flow patterns, highlighting the genus's adaptability and diversity.

Wolbachia endosymbionts in two Anopheles species indicates independent acquisitions and lack of prophage elements

This study reports two high-density Wolbachia strains in Anopheles species, showing independent acquisitions and limited prophage elements, with genomic analysis revealing metabolic completeness and cytoplasmic incompatibility factors.

Genomic and antigenic diversity of carried Klebsiella pneumoniae isolates mirrors that of invasive isolates in Blantyre, Malawi

This study compares genomic and antigenic diversity of colonizing and invasive Klebsiella pneumoniae isolates in Blantyre, Malawi, finding similar population structures and highlighting the potential of colonizing isolates for vaccine development.

Genomic analysis of extended-spectrum beta-lactamase (ESBL) producing Escherichia coli colonising adults in Blantyre, Malawi reveals previously undescribed diversity.

This study sequenced ESBL-producing E. coli from Malawi to assess genetic diversity and AMR determinants, revealing locally circulating subclades and carbapenemase genes.

YhcB coordinates peptidoglycan and LPS biogenesis with phospholipid synthesis during Escherichia coli cell growth.

This study identifies YhcB as a coordinator of peptidoglycan, LPS, and phospholipid synthesis in E. coli, revealing its role in envelope stability and cell size control.

Genomic and microscopic evidence of stable high density and maternally inherited Wolbachia infections in Anopheles mosquitoes

The paper identifies high-density, maternally inherited Wolbachia infections in Anopheles mosquitoes using genomic and microscopic evidence, suggesting their potential for biocontrol.

Piperacillin/tazobactam resistant, cephalosporin susceptible Escherichia coli bloodstream infections are driven by multiple acquisition of resistance across diverse sequence types

The paper identifies genetic diversity and resistance mechanisms in E. coli with piperacillin/tazobactam resistance but third-generation cephalosporin susceptibility.

BonA from Acinetobacter baumannii forms a divisome-localized decamer that supports outer envelope function

This study identifies BonA as an outer membrane protein in Acinetobacter baumannii that forms a transient decamer, supports outer envelope function, and is involved in cell division and motility.

Structure-function analyses of dual-BON domain protein DolP identifies phospholipid binding as a new mechanism for protein localisation

This study identifies phospholipid binding as a mechanism for DolP localization, revealing its structure and function in Gram-negative bacteria.

Microbial interactions in the mosquito gut determine Serratia colonization and blood feeding propensity.

This study investigates how microbial interactions in the mosquito gut affect Serratia colonization and blood feeding behavior in Ae. aegypti.

Gut-associated bacteria invade the midgut epithelium of Aedes aegypti and stimulate innate immunity and suppress Zika virus infection in cells.

This study shows gut bacteria invade mosquito cells, activate immune pathways, and reduce Zika virus infection.

Kaptive Web: user-friendly capsule and lipopolysaccharide serotype prediction for Klebsiella genomes

Kaptive Web is an online tool for typing Klebsiella K and O loci in genome assemblies, showing extensive diversity in these loci among clinical isolates.