Author

M. Delling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Pinedo· 2 shared K. Ha· 2 shared A. P. Nievergelt· 1 shared C. H. Park· 1 shared C. J. Ye· 1 shared D. Diener· 1 shared D. R. Diener· 1 shared D. Raleigh· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

A. Pinedo

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ADPKD-Causing Missense Variants in Polycystin-1 Disrupt Cell Surface Localization or Polycystin Channel Function

K. Ha, G. B. Loeb, M. Park, M. Gupta, Y. Akiyama, J. Argiris, A. Pinedo, C. H. Park, N. Brandes, F. Ritu, C. J. Ye, J. F. Reiter, M. Delling

This study classifies ADPKD-causing missense variants in polycystin-1 into two categories based on their effects on cell surface localization or ion channel function and suggests small-molecule therapies.

bioRxiv · Dec 4, 2023Cell Biology

Testing the ion-current model for flagellar length sensing and IFT regulation

H. Ishikawa, J. Moore, D. Diener, M. Delling, W. F. Marshall

This study tests the ion-current model for flagellar length sensing by measuring Ca2+ levels and IFT injection in Chlamydomonas, finding no support for the model's predictions.

bioRxiv · Aug 20, 2022Cell Biology

The cilia enriched oxysterol 7β,27-DHC is required for polycystin activation

K. Ha, N. Mundt, P. Bisignano, A. Pinedo, E. Cao, J. Reiter, D. Raleigh, M. Delling

This study identifies 7β,27-DHC as a critical oxysterol required for polycystin complex activation in cilia, revealing a lipid-mediated regulatory mechanism for ADPKD.

bioRxiv · Apr 13, 2022 · PreprintPhysiology

Intraflagellar transport trains can turn around without the ciliary tip complex

A. P. Nievergelt, I. Zykov, D. R. Diener, T.-O. Buchholz, M. Delling, S. Diez, F. Jug, L. Stepanek, G. Pigino

This study shows that intraflagellar transport trains can turn around without a dedicated calcium-dependent tip complex in Chlamydomonas reinhardtii.

bioRxiv · Mar 19, 2021 · PreprintCell Biology