Author

N. de Franceschi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Assay:electronic health records· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

W. Weissenhorn· 4 shared P. Bassereau· 3 shared S. Maity· 3 shared N. Miguet· 2 shared S. Mangenot· 2 shared W. Roos· 2 shared A. Bertin· 1 shared A. Blanch Jover· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersCell Biology

W. Weissenhorn

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural basis of CHMP2A-CHMP3 ESCRT-III polymer assembly and membrane cleavage

K. Azad, D. Guilligay, C. Boscheron, S. Maity, N. De Franceschi, G. Sulbaran, G. Effantin, H. Wang, J.-P. Kleman, P. Bassereau, G. Schoehn, W. Roos, A. Desfosses, W. Weissenhorn

This study presents cryo-EM structures of CHMP2A-CHMP3 ESCRT-III filaments and shows they constrict and cleave membrane tubes through electrostatic interactions and VPS4-mediated remodeling.

bioRxiv · Apr 12, 2022Cell Biology

The archaeal division protein CdvB1 assembles into polymers that are depolymerized by CdvC

A. Blanch Jover, N. De Franceschi, D. Fenel, W. Weissenhorn, C. Dekker

This study shows that CdvB1 forms filamentous polymers that are depolymerized by CdvC, and that polymerization and membrane binding are mutually exclusive.

bioRxiv · Oct 7, 2021 · PreprintBiochemistry

Human ESCRT-III Polymers Assemble on Positively Curved Membranes and Induce Helical Membrane Tube Formation

A. Bertin, N. de Franceschi, E. de la Mora, S. maity, N. Miguet, A. di Cicco, W. H. Roos, S. Mangenot, W. Weissenhorn, P. Bassereau

This study investigates how ESCRT-III proteins assemble on curved membranes and induce helical tube formation using in vitro experiments and imaging techniques.

bioRxiv · Nov 20, 2019Cell Biology

The ESCRT-III Isoforms CHMP2A And CHMP2B Display Different Effects On Membranes Upon Polymerization

M. Alqabandi, N. de Franceschi, N. Miguet, S. Maity, M. Bally, W. Roos, W. Weissenhorn, P. Bassereau, S. Mangenot

This study compares the membrane interactions of CHMP2A and CHMP2B, finding they have distinct lipid binding preferences and mechanical effects on membranes.

bioRxiv · Sep 3, 2019Biophysics