Author

N. Gros

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

D. Muriaux· 3 shared A. Neyret· 2 shared C. Chable-Bessia· 2 shared M. Henaut· 2 shared P. Merida· 2 shared S. Lyonnais· 2 shared A. Bourdin· 1 shared A. F. Petit· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

D. Muriaux

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Human airway ex vivo models: new tools to study the airway epithelial cell response to SARS-CoV-2 infection

S. Assou, E. Ahmed, L. Morichon, A. Nasri, F. Foisset, C. Bourdais, N. Gros, S. Wong, A. F. Petit, I. Vachier, D. Muriaux, A. Bourdin, J. De Vos

The paper uses ALI and iALI models to study SARS-CoV-2 infection effects on airway epithelial cells, finding increased interferon and inflammatory gene expression and epithelial damage.

bioRxiv · Apr 15, 2023 · PreprintCell Biology

Low selectivity index of ivermectin and macrocyclic lactones on SARS-CoV2 replication in vitro argues against their therapeutic use for COVID-19.

C. Chable-Bessia, C. Boulle, A. Neyret, J. M. Swain, M. Henaut, P. Merida, N. Gros, A. Makinson, S. Lyonnais, C. B. Chesnais, D. Muriaux

This study evaluates the anti-SARS-CoV-2 activity of ivermectin and other macrocyclic lactones in vitro, finding low selectivity indices that suggest limited therapeutic potential for COVID-19.

bioRxiv · Nov 1, 2021 · PreprintMicrobiology

The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive-strand RNA viruses

B. Bonaventure, A. Rebendenne, F. Garcia de Gracia, J. McKellar, S. Gracias, E. Labaronne, M. Tauziet, A. L. Chaves Valadao, E. Bernard, L. Briant, N. Gros, W. Djilli, M. Arnaud-Arnould, V. Courgnaud, H. Parrinello, , C. Goujon

This study identifies DDX42 as an intrinsic antiviral inhibitor that restricts HIV-1 and other positive-strand RNA viruses but not negative-strand RNA viruses.

bioRxiv · Oct 28, 2020Microbiology

Direct visualization of native infectious SARS-CoV-2 and its inactivation forms using high resolution Atomic Force Microscopy

S. Lyonnais, M. Henaut, A. Neyret, P. Merida, N. Gros, C. Chable-Bessia, D. Muriaux

This paper uses atomic force microscopy to visualize native and inactivated SARS-CoV-2 viruses, showing their structural changes after formaldehyde treatment.

bioRxiv · Oct 23, 2020 · PreprintMicrobiology