Author

B. Bonaventure

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 6

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 6 Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Goujon· 4 shared A. L. Chaves Valadao· 3 shared A. Rebendenne· 3 shared J. McKellar· 3 shared M. Arnaud-Arnould· 3 shared M. Tauziet· 3 shared O. Moncorge· 3 shared F. Garcia de Gracia· 2 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersMicrobiology

C. Goujon

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Distinct chikungunya virus polymerase palm subdomains contribute to virus replication and virion assembly

M.-F. Martin, B. Bonaventure, N. E. McCray, O. B. Peersen, K. Rozen-Gagnon, K. Stapleford

This study identifies key residues in the CHIKV nsP4 polymerase palm and ring finger domains that influence replication, genetic stability, and assembly across different hosts.

bioRxiv · Jan 15, 2024 · PreprintMicrobiology

Pharmacological perturbation of intracellular dynamics as a SARS-CoV-2 antiviral strategy

W. Bakhache, E. Partiot, V. Lucansky, Y. Bare, B. Bonaventure, C. Goujon, C. Bories, M. S. Deffieu, R. Gaudin

This paper identifies RG10 and RG10b as potent antiviral compounds against SARS-CoV-2 by perturbing ER/virus dynamics, with RG10b showing improved stability and efficacy.

bioRxiv · Sep 10, 2021 · PreprintMicrobiology

SARS-CoV-2 hijacks p38β/MAPK11 to promote viral protein translation

C. A. Higgins, B. E. Nilsson-Payant, A. Kurland, C. Ye, T. M. Yaron, J. L. Johnson, B. Bonaventure, P. Adhikary, I. Golynker, B. R. Rosenberg, O. Danziger, M. Panis, L. C. Cantley, L. Martinez-Sobrido, B. R. tenOever, J. R. Johnson

This study identifies p38β as a critical host factor for SARS-CoV-2 replication and shows that inhibiting it reduces viral replication and cytokine production.

bioRxiv · Aug 20, 2021 · PreprintMicrobiology

Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal coronaviruses

A. Rebendenne, P. Roy, B. Bonaventure, A. L. Chaves Valadao, L. Desmarets, Y. Rouille, M. Tauziet, M. Arnaud-Arnould, D. Giovannini, Y. Lee, P. DeWeirdt, M. Hegde, F. Garcia de Gracia, J. McKellar, M. Wencker, , C. Goujon

The paper performs bidirectional CRISPR screens to identify host factors regulating SARS-CoV-2, MERS-CoV, and seasonal coronaviruses, revealing new anti-viral proteins and general coronavirus cofactors.

bioRxiv · May 19, 2021Microbiology

The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive-strand RNA viruses

B. Bonaventure, A. Rebendenne, F. Garcia de Gracia, J. McKellar, S. Gracias, E. Labaronne, M. Tauziet, A. L. Chaves Valadao, E. Bernard, L. Briant, N. Gros, W. Djilli, M. Arnaud-Arnould, V. Courgnaud, H. Parrinello, , C. Goujon

This study identifies DDX42 as an intrinsic antiviral inhibitor that restricts HIV-1 and other positive-strand RNA viruses but not negative-strand RNA viruses.

bioRxiv · Oct 28, 2020Microbiology

SARS-CoV-2 replication triggers an MDA-5-dependent interferon production which is unable to efficiently control replication

A. Rebendenne, A. L. Chaves Valadao, M. Tauziet, G. Maarifi, B. Bonaventure, R. Planes, J. McKellar, S. Nisole, M. Arnaud-Arnould, O. Moncorge, C. Goujon

This study shows that SARS-CoV-2 triggers MDA-5-dependent interferon production in human cells, but this response fails to control viral replication.

bioRxiv · Oct 28, 2020Microbiology