Author

F. Garcia de Gracia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:genetic perturbation / CRISPR· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1

Frequent Co-Authors

A. L. Chaves Valadao· 3 shared A. Rebendenne· 3 shared C. Goujon· 3 shared J. McKellar· 3 shared M. Arnaud-Arnould· 3 shared M. Tauziet· 3 shared O. Moncorge· 3 shared B. Bonaventure· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

A. L. Chaves Valadao

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Human MX1 orchestrates the cytoplasmic sequestration of neo-synthesized influenza A virus vRNPs

J. McKellar, F. Garcia de Gracia, C. Aube, A. L. Chaves Valadao, M. Tauziet, M. Arnaud-Arnould, A. Rebendenne, A. Neyret, E. Labaronne, E. P. Ricci, B. Delaval, R. Gaudin, N. Naffakh, S. Gallois-Montbrun, O. Moncorge, C. Goujon

This study shows human MX1 restricts influenza A virus by sequestering vRNPs in cytoplasmic clusters via dynein and microtubules, reducing viral production.

bioRxiv · Feb 22, 2024 · PreprintMicrobiology

Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal coronaviruses

A. Rebendenne, P. Roy, B. Bonaventure, A. L. Chaves Valadao, L. Desmarets, Y. Rouille, M. Tauziet, M. Arnaud-Arnould, D. Giovannini, Y. Lee, P. DeWeirdt, M. Hegde, F. Garcia de Gracia, J. McKellar, M. Wencker, , C. Goujon

The paper performs bidirectional CRISPR screens to identify host factors regulating SARS-CoV-2, MERS-CoV, and seasonal coronaviruses, revealing new anti-viral proteins and general coronavirus cofactors.

bioRxiv · May 19, 2021Microbiology

The DEAD box RNA helicase DDX42 is an intrinsic inhibitor of positive-strand RNA viruses

B. Bonaventure, A. Rebendenne, F. Garcia de Gracia, J. McKellar, S. Gracias, E. Labaronne, M. Tauziet, A. L. Chaves Valadao, E. Bernard, L. Briant, N. Gros, W. Djilli, M. Arnaud-Arnould, V. Courgnaud, H. Parrinello, , C. Goujon

This study identifies DDX42 as an intrinsic antiviral inhibitor that restricts HIV-1 and other positive-strand RNA viruses but not negative-strand RNA viruses.

bioRxiv · Oct 28, 2020Microbiology