Author

N. Hubner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. A. Hyman· 1 shared A. Bauer· 1 shared A. Brown· 1 shared A. Chhabra· 1 shared A. Goodale· 1 shared A. Heuser· 1 shared A. L. Condurat· 1 shared A. Rapp· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. A. Hyman

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Translation of non-canonical open reading frames as a cancer cell survival mechanism in childhood medulloblastoma

D. A. Hofman, J. Ruiz-Orera, I. Yannuzzi, R. Murugesan, A. Brown, K. R. Clauser, A. L. Condurat, J. T. van Dinter, S. A. G. Engels, A. Goodale, J. van der Lugt, T. Abid, L. Wang, K. N. Zhou, J. Vogelzang, , J. R. Prensner

The paper investigates non-canonical ORF translation in medulloblastoma, identifying ASNSD1-uORF as critical for cell survival through interactions with the prefoldin-like chaperone complex.

bioRxiv · May 4, 2023Cancer Biology

Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators

J. Kuhnisch, S. Theisen, J. Dartsch, R. Fritsche-Guenther, M. Kirchner, B. Obermayer, A. Bauer, A.-K. Kahlert, M. Rothe, D. Beule, A. Heuser, P. Mertins, J. A. Kirwan, N. Berndt, C. A. MacRae, , S. Klaassen

This study investigates monoallelic Prdm16 mutation in mice, revealing sex-specific cardiac metabolic dysregulation and identifying Pyroxd2 and Pbxip1 as novel metabolic regulators.

bioRxiv · Jan 10, 2023 · PreprintPathology

SAMHD1 controls innate immunity by regulating condensation of immunogenic self RNA

S. Maharana, S. Kretschmer, S. Hunger, X. Yan, D. Kuster, S. Traikov, T. Zillinger, N. Chappidi, N. Lucas, K. I. Maser, H. Maatz, A. Rapp, V. Marchand, V. Iyer, A. Chhabra, , M. A. Lee-Kirsch

This study shows SAMHD1 regulates innate immunity by controlling RNA condensation, preventing immune recognition of self RNA and reducing inflammation.

bioRxiv · Jul 12, 2022Immunology