Author

N. K. Yiew

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Pharmacology & Toxicology· 1

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

B. N. Finck· 1 shared E. U. Yee· 1 shared F. D. Allard· 1 shared J. H. Vazquez· 1 shared J. R. Price· 1 shared K. S. McCommis· 1 shared L. P. James· 1 shared M. R. Martino· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. N. Finck

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintJun 14, 2022

Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult in mice

N. K. Yiew, J. H. Vazquez, M. R. Martino…·M. R. McGill

This study shows that loss of both MPC and ALT2 increases susceptibility to oxidative stress and worsens liver injury in mice, while ALT2 induction reduces APAP toxicity.

DOI 10.1101/2022.06.14.495517

mousebulk RNA-seq

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