Author

M. R. McGill

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

B. N. Finck· 2 shared E. U. Yee· 2 shared F. D. Allard· 2 shared J. H. Vazquez· 2 shared L. P. James· 2 shared S. Kennon-McGill· 2 shared A. K. Smith· 1 shared C. A. Hunt· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPharmacology & Toxicology

B. N. Finck

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4 papers

Recent·Most cited

Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult in mice

N. K. Yiew, J. H. Vazquez, M. R. Martino, S. Kennon-McGill, J. R. Price, F. D. Allard, E. U. Yee, L. P. James, K. S. McCommis, B. N. Finck, M. R. McGill

This study shows that loss of both MPC and ALT2 increases susceptibility to oxidative stress and worsens liver injury in mice, while ALT2 induction reduces APAP toxicity.

bioRxiv · Jun 14, 2022 · PreprintPharmacology & Toxicology

Exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating hepatic interleukin-6 signaling through inter-organ crosstalk

M. M. Clemens, S. Kennon-McGill, J. H. Vazquez, O. W. Stephens, E. A. Peterson, D. J. Johann, F. D. Allard, E. U. Yee, S. S. McCullough, L. P. James, B. N. Finck, M. R. McGill

This study shows exogenous phosphatidic acid reduces acetaminophen-induced liver injury in mice by activating hepatic IL-6 signaling through inter-organ crosstalk, but does not enhance liver regeneration.

bioRxiv · Dec 22, 2020Pharmacology & Toxicology

Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms

A. K. Smith, G. E. P. Ropella, M. R. McGill, P. Krishnan, L. Dutta, R. C. Kennedy, H. Jaeschke, C. A. Hunt

The paper challenges four model mechanisms of ALT release from hepatocytes following APAP exposure in mice, finding one mechanism matches all validation targets quantitatively.

bioRxiv · Dec 24, 2019Pharmacology & Toxicology

Carpenter ants use diverse antennae sampling strategies to track odor trails

R. W. Draft, M. R. McGill, V. Kapoor, V. N. Murthy

This study uses high-resolution videography to show carpenter ants use distinct antennae sampling strategies for odor trail tracking, with non-redundant roles for left and right antennae.

bioRxiv · May 21, 2018Animal Behavior & Cognition