Author

N. Lemus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:genetic perturbation / CRISPR· 1 Organism:non-human primate· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. Garcia-Sastre· 2 shared F. Krammer· 2 shared I. Gonzalez-Dominguez· 2 shared I. Mena· 2 shared L. Coughlan· 2 shared M. Schotsaert· 2 shared P. Palese· 2 shared S. McCroskery· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

A. Garcia-Sastre

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs

E. C. Stahl, J. K. Sabo, M. H. Kang, R. Allen, E. Applegate, S. E. Kim, Y. Kwon, A. Seth, N. Lemus, V. Salinas-Rios, K. Soczek, M. Trinidad, L. T. Vo, C. Jeans, A. Wozniak, , J. A. Doudna

This study demonstrates that minimally immunogenic Cas9 RNPs delivered via convection enhanced delivery can edit mouse striatal neurons with reduced immune responses compared to AAV-delivered Cas9.

bioRxiv · Apr 13, 2023Bioengineering

Trivalent NDV-HXP-S vaccine protects against phylogenetically distant SARS-CoV-2 variants of concern in mice

I. Gonzalez-Dominguez, J. L. Martinez, S. Slamanig, N. Lemus, Y. Liu, T. Y. Lai, J. M. Carreno, G. Singh, G. Singh, M. Schotsaert, I. Mena, S. McCroskery, L. Coughlan, F. Krammer, A. Garcia-Sastre, , W. Sun

The paper tests a trivalent NDV-HXP-S vaccine against SARS-CoV-2 variants in mice, showing increased protection and cross-neutralizing antibodies against Omicron.

bioRxiv · Mar 21, 2022Immunology

A Newcastle disease virus-vector expressing a prefusion-stabilized spike protein of SARS-CoV-2 induces protective immune responses against prototype virus and variants of concern in mice and hamsters

W. Sun, Y. Liu, F. Amanat, I. Gonzalez-Dominguez, S. McCroskery, S. Slamanig, L. Coughlan, V. Rosado, N. Lemus, S. Jangra, R. Rathnasinghe, M. Schotsaert, J. Martinez, K. Sano, I. Mena, , P. Palese

This study develops a Newcastle disease virus-based vaccine expressing a prefusion-stabilized SARS-CoV-2 spike protein, showing strong immune responses and cross-neutralization against variants in mice and hamsters.

bioRxiv · Jul 6, 2021 · PreprintImmunology