Author

N. Paolocci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

E. G. Lakatta· 2 shared G. Keceli· 2 shared J.-H. Qu· 2 shared K. V. Tarasov· 2 shared S. Jun· 2 shared Y. S. Tarasova· 2 shared A. E. Lyashkov· 1 shared A. Gemignani· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersPhysiology

E. G. Lakatta

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Spatial analysis of NOS2 and COX2 interaction with T-effector cells reveals immunosuppressive landscapes associated with poor outcome in ER- breast cancer patients

L. A. Ridnourl, R. Y. Cheng, W. F. Heinz, M. Pore, A. L. Gonzalez, E. L. Femino, R. Moffat, A. L. Wink, F. Imtiaz, L. Coutinho, D. Butcher, E. F. Edmondson, C. Rangel, S. T. Wong, S. Lipkowitz, , D. A. Wink

The paper identifies spatial interactions between NOS2, COX2, and T-effector cells in ER- breast cancer, linking these patterns to poor patient outcomes and suggesting potential therapeutic strategies.

bioRxiv · Dec 21, 2023 · PreprintCancer Biology

Ischemia/Reperfusion Injury and Oxidative Stress Impair Cardiac Desmin Proteostasis

Z. Li, S. Jun, K. K. Singh, P. J. Calhoun, G. Keceli, K. Patel, H. Kadioglu, N. Paolocci, G. Agnetti

This study investigates how oxidative stress and reperfusion injury affect desmin proteostasis, identifying mechanisms to reduce toxic desmin aggregates and improve cardiac function.

bioRxiv · May 9, 2023 · PreprintBiochemistry

A Remarkable Adaptive Paradigm Of Heart Performance And Protection Emerges In Response To The Constitutive Challenge Of Marked Cardiac-Specific Overexpression Of Adenylyl Cyclase Type 8

K. V. Tarasov, K. Chakir, D. R. Riordon, A. E. Lyashkov, I. Ahmet, M. G. Perino, A. J. Silvester, J. Zhang, M. Wang, Y. O. Lukyanenko, J.-H. Qu, M. C.-R. Barrera, M. Juhaszova, Y. S. Tarasova, B. Ziman, , E. G. Lakatta

This study shows that cardiac-specific overexpression of AC8 in mice leads to adaptive cardiac changes resembling cancer-like survival mechanisms without heart failure.

bioRxiv · May 20, 2022Physiology

Cardiac adenylyl cyclase type 8 overexpression increases locomotor activity in mice by modulating EEG-gamma oscillations

J. Agrimi, D. Menicucci, J.-H. Qu, C. Mackey, M. Laurino, L. Hasnain, R. A. McDevit, Y. S. Tarasova, K. V. Tarasov, D. B. Hoover, A. Gemignani, N. Paolocci, E. G. Lakatta

This study shows that cardiac AC8 overexpression in mice increases locomotion via enhanced gamma oscillations linked to dopamine and GABA-A receptor activity.

bioRxiv · Jul 19, 2021 · PreprintPhysiology