Author

N. R. Klatt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:metagenomics· 3 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

L. Schifanella· 3 shared A. Velez· 2 shared C. A. Broedlow· 2 shared M. Gale· 2 shared T. Schroeder· 2 shared A. D. Swafford· 1 shared A. Gustin· 1 shared A. S. Havulinna· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersMicrobiology

L. Schifanella

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SARS-CoV-2 infection is associated with intestinal permeability, systemic inflammation, and microbial dysbiosis in hospitalized COVID-19 patients

C. M. Basting, R. Langat, C. A. Broedlow, C. Guerrero, T. D. Bold, M. Bailey, A. Velez, T. Schroeder, J. Short-Miller, R. Cromarty, Z. Mayer, P. J. Southern, T. W. Schacker, S. E. Safo, C. T. Bramante, , N. R. Klatt

This study examines the impact of SARS-CoV-2 infection on intestinal permeability, systemic inflammation, and microbial dysbiosis in hospitalized patients, finding associations between specific microbial changes and disease severity.

bioRxiv · Dec 7, 2023 · PreprintMicrobiology

Elevated peripheral and nervous system inflammation is associated with decreased short-chain fatty acid levels in Zika-virus infected macaques

C. Miller, J. Manuzak, A. Gustin, C. Basting, R. Cheu, T. Schroeder, A. Velez, C. Driscoll, J. Tisoncik-Go, L. Schifanella, T. Hensley-McBain, C. Evandy, E. Smith, D. Bratt, J. Smedley, , N. R. Klatt

This study links reduced short-chain fatty acid levels with elevated inflammation in Zika-virus infected macaques, suggesting microbial dysfunction contributes to CNS and systemic inflammation.

bioRxiv · Jul 25, 2023 · PreprintMicrobiology

High-risk microbial signatures are associated with severe parasitemia in controlled Plasmodium infections of both humans and rhesus macaques

A. T. Gustin, C. A. Broedlow, K. Hager, E. Coronado, S. Wangari, N. Iwayama, C. Y. Ahrens, W. D. Garrison, K. A. Guerriero, K. De Paris, M. Gale, N. R. Klatt, J. G. Kublin, J. A. Manuzak

The paper identifies a high-risk microbial signature in the gut microbiome associated with severe parasitemia in both humans and rhesus macaques during controlled Plasmodium infections.

bioRxiv · Sep 6, 2022Microbiology

Bacterial modification of the host glycosaminoglycan heparan sulfate modulates SARS-CoV-2 infectivity

C. Martino, B. P. Kellman, D. R. Sandoval, T. M. Clausen, C. A. Marotz, S. J. Song, S. Wandro, L. S. Zaramela, R. A. Salido Benitez, Q. Zhu, E. Armingol, Y. Vazquez-Baeza, D. McDonald, J. T. Sorrentino, B. Taylor, , R. Knight

This study shows that commensal bacteria modify heparan sulfate, reducing SARS-CoV-2 spike protein binding and that this bacterial presence decreases with age, increasing COVID-19 susceptibility.

bioRxiv · Aug 17, 2020 · PreprintMicrobiology