Author

O. J. Wilkinson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Approach:biophysical modeling· 2 Research Focus:chromatin & epigenetic regulation· 2 Assay:DNA methylation· 2 Organism:human· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

M. S. Dillingham· 3 shared D. B. Wigley· 2 shared F. Moreno-Herrero· 2 shared A. Martin-Gonzalez· 1 shared C. Aicart-Ramos· 1 shared C. Feyerherm· 1 shared E. E. Fletcher· 1 shared F. Balaguer-Perez· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

M. S. Dillingham

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

DNA binding and bridging by human CtIP in the healthy and diseased states

S. Lokanathan Balaji, S. De Braganca, F. Balaguer-Perez, S. Northall, O. J. Wilkinson, C. Aicart-Ramos, F. Sobott, N. Seetaloo, F. Moreno-Herrero, M. S. Dillingham

This study investigates the DNA binding and bridging activities of CtIP in healthy and diseased states, identifying a C-terminal DNA-binding domain and showing that tetramerization is required for DNA bridging.

bioRxiv · Dec 14, 2023 · PreprintBiochemistry

Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub

M. Wilkinson, O. J. Wilkinson, C. Feyerherm, E. E. Fletcher, D. B. Wigley, M. S. Dillingham

The paper presents structural and biochemical analysis of two phage proteins that inhibit or co-opt the bacterial RecBCD complex to evade host immunity.

bioRxiv · Sep 12, 2022Biochemistry

Human CtIP forms a tetrameric dumbbell-shaped particle which binds and bridges complex DNA end structures for double-strand break repair

O. J. Wilkinson, A. Martin-Gonzalez, H. J. Kang, S. J. Northall, D. B. Wigley, F. Moreno-Herrero, M. S. Dillingham

This study shows human CtIP forms a tetramer that binds and bridges DNA ends, facilitating resection for double-strand break repair.

bioRxiv · Sep 5, 2018Biochemistry