Author

N. Vallavoju

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. B. Beeler· 1 shared A. R. Ivanov· 1 shared B. Bhattacharya· 1 shared C. M. Woo· 1 shared C.-F. Chang· 1 shared E. Waligurski· 1 shared H. A. Flaxman· 1 shared I. Kramnik· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. B. Beeler

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2 papers

Recent·Most cited

The Cyclimids: Degron-inspired cereblon binders for targeted protein degradation

S. Ichikawa, N. C. Payne, W. Xu, C.-F. Chang, N. Vallavoju, S. Frome, H. A. Flaxman, R. Mazitschek, C. M. Woo

This study introduces cyclimids, degrons derived from CRBN, which show improved selectivity and potency in targeted protein degradation by forming ternary complexes with CRBN and substrates.

bioRxiv · Apr 22, 2023Biochemistry

Channeling macrophage polarization via selective translation inhibition by rocaglates increases macrophage resistance to Mycobacterium tuberculosis

S. Chatterjee, S. M. Yabaji, B. Bhattacharya, E. Waligurski, N. Vallavoju, S. Ray, L. E. Brown, A. B. Beeler, A. R. Ivanov, L. Kobzik, J. A. Porco, I. Kramnik

This study shows rocaglates shift macrophage polarization toward M1-like by inhibiting IL-4 response and enhancing resistance to Mycobacterium tuberculosis.

bioRxiv · Aug 31, 2020 · PreprintImmunology