Author

S. Ichikawa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Katsuyama· 1 shared A. Kihara· 1 shared C. M. Woo· 1 shared C.-F. Chang· 1 shared D. Usukura· 1 shared H. A. Flaxman· 1 shared H. Tsutsui· 1 shared I. Shiina· 1 shared

Activity by Year

2023-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. Katsuyama

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Author profile →

3 papers

Recent·Most cited

Determining the structure of protein-bound ceramides, essential lipids for skin barrier function

Y. Ohno, T. Nakamura, T. Iwasaki, A. Katsuyama, S. Ichikawa, A. Kihara

This study identifies the structure of protein-bound ceramides as Cys-bound epoxy-enone ceramides through chemical and biochemical analyses.

iScience · Nov 1, 2023Peer-reviewedCell Biology

Brefeldin A and M-COPA block the export of RTKs from the endoplasmic reticulum via simultaneous inactivation of ARF1, ARF4, and ARF5

M. Natsume, M. Niwa, S. Ichikawa, T. Okamoto, H. Tsutsui, D. Usukura, T. Murata, R. Abe, M. Shimonaka, T. Nishida, I. Shiina, Y. Obata

This study shows that BFA and M-COPA inhibit RTK export from the ER by inactivating ARF1, ARF4, and ARF5, leading to cancer cell apoptosis.

bioRxiv · Oct 11, 2023Cell Biology

The Cyclimids: Degron-inspired cereblon binders for targeted protein degradation

S. Ichikawa, N. C. Payne, W. Xu, C.-F. Chang, N. Vallavoju, S. Frome, H. A. Flaxman, R. Mazitschek, C. M. Woo

This study introduces cyclimids, degrons derived from CRBN, which show improved selectivity and potency in targeted protein degradation by forming ternary complexes with CRBN and substrates.

bioRxiv · Apr 22, 2023Biochemistry