Author

N.-G. Larsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

C. Koolmeister· 3 shared F. M. Hansen· 2 shared L. S. Kremer· 2 shared M. Mann· 2 shared R. Filograna· 2 shared A. Chabes· 1 shared A. K. Nilsson· 1 shared A. Krook· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCell Biology

C. Koolmeister

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Inhibition of mammalian mtDNA transcription paradoxically activates liver fatty acid oxidation to reverse diet-induced hepatosteatosis and obesity

S. Jiang, T. Yuan, L. S. Kremer, F. A. Rosenberger, F. M. Hansen, M. Borg, D. Rubalcava-Gracia, M. Mennuni, R. Filograna, D. Alsina, J. Misic, C. Koolmeister, L. Ren, O. Andersson, A. Unger, , N.-G. Larsson

The paper shows that inhibiting mitochondrial DNA transcription in mice increases fatty acid oxidation, reducing obesity and liver fat while decreasing oxidative phosphorylation capacity.

bioRxiv · Sep 22, 2023 · PreprintPhysiology

Parkin is not required to sustain OXPHOS function in adult mammalian tissues

R. Filograna, J. Gerlach, H.-N. Choi, G. Rigoni, M. Barbaro, M. Oscarson, S. Lee, K. Tiklova, M. Ringner, C. Koolmeister, R. Wibom, S. Riggare, I. Nennesmo, T. Perlmann, A. Wredenberg, , N.-G. Larsson

This study shows that PARKIN is not required for OXPHOS function in adult mammalian tissues, using mouse models and a patient with PARKIN deficiency.

bioRxiv · Sep 2, 2023Cell Biology

Mitochondrial phosphoproteomes are functionally specialized across tissues

M. Mann, F. M. Hansen, L. S. Kremer, O. Karayel, I. Kühl, I. Bludau, N.-G. Larsson

The paper quantitatively profiles mitochondrial proteomes and phosphoproteomes across multiple tissues in mice, revealing tissue-specific kinase and phosphatase repertoires and functional phosphorylation events.

bioRxiv · Mar 23, 2022Biochemistry

Proofreading deficiency in mitochondrial DNA polymerase does not affect total dNTP pools in mouse embryos

S. Sharma, C. Koolmeister, P. Tran, A. K. Nilsson, N.-G. Larsson, A. Chabes

The paper shows that mtDNA mutator mouse embryos with proofreading-deficient PolgD257A have normal total dNTP pools despite rapid cell division, contradicting previous claims of dNTP depletion.

bioRxiv · Mar 4, 2020Cell Biology