Nathaniel Fox Hansen

Precision Targeting of Heparan Sulfate Proteoglycans Broadly Dysregulates Survival Signaling and Metabolic Adaptation in Pancreatic Cancer

This study shows that targeting heparan sulfate proteoglycans in pancreatic cancer with bacterial heparinase III reduces survival signaling and metabolic adaptation, potentially improving therapy efficacy.

Molecular profiling of glioblastoma-derived extracellular vesicles identifies small nucleolar RNAs as candidate liquid biomarkers for radiation-induced senescence

This paper identifies small nucleolar RNAs (snoRNAs) as potential liquid biomarkers for radiation-induced senescence in glioblastoma by analyzing extracellular vesicle cargo changes.

Human placental organoids as a model to probe early gestation maternal immune dynamics

This study uses human placental organoids to investigate trophoblast subtypes' roles in modulating maternal immune responses and shows 3D culture affects immunomodulation differently than 2D culture.

Engineered 3D Hydrogel Matrices to Modulate Trophoblast Stem Cell-Derived Placental Organoid Phenotype

This study uses engineered 3D hydrogels to generate placental organoids and shows they support trophoblast viability and differentiation comparable to Matrigel.