Khyatiben V. Pathak

Precision Targeting of Heparan Sulfate Proteoglycans Broadly Dysregulates Survival Signaling and Metabolic Adaptation in Pancreatic Cancer

This study shows that targeting heparan sulfate proteoglycans in pancreatic cancer with bacterial heparinase III reduces survival signaling and metabolic adaptation, potentially improving therapy efficacy.

Serum metabolomics signatures after an acute bout of combined traditional or high-intensity tactical training in young males and females

This study compares serum metabolomics responses to traditional combined exercise and high-intensity tactical training in young adults, finding similar patterns but greater magnitude changes with traditional exercise.

Immunometabolic determinants of long-term response in leukemia patients receiving CD19 CAR T cell therapy

This study identifies immunometabolic factors in CD19 CAR T cells that predict long-term response in B-ALL patients and suggests mTOR inhibition as a strategy to enhance anti-tumor activity.