Author

Steven L. Kazmirski

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Aaron N. Chang· 1 shared Alan Robertson· 1 shared Alissa C. GossiD· 1 shared Andrew Nelson· 1 shared Angela M. CacaceiD· 1 shared Anna GrekaiD· 1 shared Anthony Accorsi· 1 shared Brianna R. Silverman· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperDevelopmental Biology

Aaron N. Chang

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2 papers

Recent·Most cited

A cargo receptor entrapment complex is a therapeutic node for genetically and clinically distinct proteinopathies

Magdalena Riedl Khursigara, Alissa C. Goss, Maria Kost‐Alimova, Keith H. Keller, Christine Danielle De Mata, Ranjithmenon Muraleedharan, Edward Ryan Collantes, Matthew Brown, Elizabeth J. Grinkevich, Felichi Mae Arines, John Lin, Patrick Byrne, Silvana Bazúa‐Valenti, Elizabeth Morici, Julie Roignot, , Anna Greka

This study identifies a therapeutic target, the entrapment complex, that clears toxic protein accumulation in distinct proteinopathies by disrupting a cargo receptor complex.

bioRxiv · Jul 13, 2026 · PreprintCell Biology

P38α Regulates Expression of DUX4 in Facioscapulohumeral Muscular Dystrophy

Luis Alejandro Rojas, Erin Valentine, Anthony Accorsi, Joseph Maglio, Ning Shen, Alan Robertson, Steven L. Kazmirski, Peter B. Rahl, Rabi Tawil, Diego Cadavid, Lorin A. Thompson, Lucienne V. Ronco, Aaron N. Chang, Angela M. Cacace, Owen B. Wallace

This study identifies p38 as a regulator of DUX4 expression in FSHD, showing that p38 inhibitors reduce DUX4 and cell death in patient-derived myotubes.

Journal of Pharmacology and Experimental Therapeutics · Jun 23, 2020Peer-reviewedDevelopmental Biology