Author

O. Klykov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 2 Research Focus:benchmarking· 1 Assay:cryo-EM· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. J. R. Heck· 2 shared A. B. Meijer· 1 shared A. J. Noble· 1 shared A. M. Raczkowski· 1 shared B. C. Amaral· 1 shared B. Carragher· 1 shared C. Borchers· 1 shared C. Emanuelsson· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

A. J. R. Heck

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Author profile →

3 papers

Recent·Most cited

Waffle Method: A general and flexible approach for FIB-milling small and anisotropically oriented samples

K. Kelley, A. M. Raczkowski, O. Klykov, P. Jaroenlak, D. Bobe, M. Kopylov, E. T. Eng, G. Bhabha, C. S. Potter, B. Carragher, A. J. Noble

The paper introduces the Waffle Method to improve cryo-FIB/SEM workflows for preparing complex biological samples for cryo-ET, demonstrating its effectiveness with various samples and hardware.

bioRxiv · Oct 28, 2020Microbiology

Flexible regions in the molecular architecture of Human fibrin clots structurally resolved by XL-MS and integrative structural modeling

O. Klykov, C. v. d. Zwaan, A. J. R. Heck, A. B. Meijer, R. A. Scheltema

This study resolves the molecular architecture of human fibrin clots using XL-MS and integrative modeling, revealing structural details of key domains and their role in lateral aggregation and clot formation.

bioRxiv · Aug 19, 2019 · PreprintBiochemistry

Cross-linking/Mass Spectrometry: A Community-Wide, Comparative Study Towards Establishing Best Practice Guidelines

C. Iacobucci, C. Piotrowski, R. Aebersold, B. C. Amaral, P. Andrews, C. Borchers, N. I. Brodie, J. E. Bruce, S. Chaignepain, J. D. Chavez, S. Claverol, J. Cox, G. Degliesposti, M. Q. Dong, N. Edinger, , Rand

This paper summarizes current XL-MS practices, compares strategies, and proposes common protocols to establish best practice guidelines for accurate and reproducible results.

bioRxiv · Sep 26, 2018 · PreprintBiochemistry