Author

P. A. Thomason

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

R. H. Insall· 3 shared L. M. Machesky· 2 shared S. Ismail· 2 shared A. J. Davidson· 1 shared C. Amato· 1 shared H. J. Spence· 1 shared J. Batista· 1 shared J. Greaves· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

R. H. Insall

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Author profile →

3 papers

Recent·Most cited

The Scar/WAVE complex drives normal actin protrusions without the Arp2/3 complex, but proline-rich domains are required

S. Buracco, S. Singh, S. Claydon, P. Paschke, L. Tweedy, J. Whitelaw, L. McGarry, P. A. Thomason, R. H. Insall

This study shows that the Scar/WAVE complex can drive normal actin protrusions without the Arp2/3 complex and that proline-rich domains are essential for actin nucleation.

bioRxiv · May 14, 2022 · PreprintCell Biology

WASP restricts active Rac to maintain cells’ front-rear polarisation

C. Amato, P. A. Thomason, A. J. Davidson, K. Swaminathan, S. Ismail, L. M. Machesky, R. H. Insall

This study shows WASP restricts active Rac to the front of cells to maintain front-rear polarity, but its interaction with Rac is not required for actin polymerization.

bioRxiv · Apr 10, 2019Cell Biology

CYRI (FAM49) proteins are local inhibitors of Scar/WAVE induced lamellipodia that bind directly to active Rac1

L. Fort, J. Batista, P. A. Thomason, H. J. Spence, J. Greaves, K. J. Martin, K. I. Anderson, P. Brown, S. Lilla, M. P. Neilson, P. Tafelmeyer, S. Zanivan, S. Ismail, N. C. O. Tomkinson, L. H. Chamberlain, , L. M. Machesky

This study identifies CYRI proteins as local inhibitors of Scar/WAVE-induced lamellipodia that bind to active Rac1, regulating protrusion size and complexity.

bioRxiv · Nov 29, 2017Cell Biology