P. Glaser

Chance favors the prepared genomes: horizontal transfer shapes the emergence of antibiotic resistance mutations in core genes.

This study shows that horizontal gene transfer influences the likelihood of acquiring antibiotic resistance mutations in core genes of E. coli.

Evo-Scope: Fully automated assessment of correlated evolution on phylogenetic trees

Evo-Scope is a fast, automated pipeline to assess correlated evolution on phylogenetic trees, improving previous tools and analyzing antibiotic resistance mutations in Streptococcus pneumoniae.

Carbapenem heteroresistance of KPC-producing Klebsiella pneumoniae results from tolerance, persistence and resistance.

The paper investigates carbapenem heteroresistance in KPC-producing Klebsiella pneumoniae, revealing that it arises from tolerance, persistence, and resistance mechanisms.

Specificities and commonalities of carbapenemase producing Escherichia coli isolated in France from 2012 to 2015.

This study characterizes the spread and genetic diversity of carbapenemase-producing Escherichia coli in France from 2012 to 2015, identifying dominant lineages and plasmid-mediated carbapenemase dissemination.

The cnf1 gene is associated to an expanding Escherichia coli ST131 H30Rx/C2 sublineage and confers a competitive advantage for host colonization

This study identifies the cnf1 gene's role in enhancing host colonization by ST131-H30Rx/C2 E. coli, driving its global spread alongside antibiotic resistance genes.

A quantitative approach to easily characterize and predict cell death and escape to β-lactam treatments

The paper develops a mathematical model to predict bacterial response to β-lactam antibiotics by integrating cellular heterogeneity and filamentation, showing it can reconcile growth and CFU data for ESBL-producing E. coli.

Evolution of VIM-1 producing Klebsiella pneumoniae isolates from a hospital outbreak reveals the genetic bases of the loss of the urease-positive identification character

The paper analyzes the evolution of a multidrug-resistant K. pneumoniae outbreak, identifying genetic changes leading to antibiotic resistance and urease loss.

The CovR regulatory network drives the evolution of Group B Streptococcus virulence

This study characterizes the CovR regulatory network in Group B Streptococcus, showing its role in virulence gene regulation and strain-specific adaptations.

Drivers of ESBL-producing Escherichia coli dynamics in calf fattening farms: a modelling study

This study models ESBL-EC dynamics in veal calf farms, finding that within-farm transmission and AMU influence carriage duration and prevalence.

Dynamics of Livestock-Associated Methicillin Resistant Staphylococcus aureus in pig farms networks: insight from mathematical modeling and French data

The paper models LA-MRSA spread in French pig farms, showing that targeting central farms reduces prevalence and identifies high indegree farms as best for surveillance of new strains.

Stepwise evolution and convergent recombination underlie the global dissemination of carbapenemase-producing Escherichia coli

The paper investigates the molecular epidemiology of carbapenemase-producing Escherichia coli, identifying key genetic factors and recombination events driving their global spread.

Inference of significant microbial interactions from longitudinal metagenomics sequencing data

The paper infers microbial interactions from longitudinal metagenomics data, finding differences in interaction patterns between healthy children and T1D progressors.

Demographic fluctuation of community-acquired antibiotic-resistant Staphylococcus aureus lineages: potential role of flimsy antibiotic exposure

The paper investigates how low-level antibiotic exposure influences the expansion of two CA-MRSA lineages by reversing the fitness cost of antibiotic resistance.