Author

P. Kanchanawong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 9

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 7 Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Assay:imaging· 4 Approach:microscopy & imaging analysis· 4 Organism:mouse· 4 Research Focus:development & morphogenesis· 2 Organism:human· 2

Frequent Co-Authors

B. C. Low· 2 shared H. T. Ong· 2 shared K. Jain· 2 shared M. P. Sheetz· 2 shared R. Changede· 2 shared Y. Toyama· 2 shared A. Bershadsky· 1 shared A. D. Bershadsky· 1 shared

Activity by Year

2018-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

B. C. Low

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Nano-clusters of ligand-activated integrins organize immobile, signalling active, nano-clusters of phosphorylated FAK required for mechanosignalling in focal adhesions

K. Jain, R. F. Minhaj, P. Kanchanawong, M. P. Sheetz, R. Changede

This study shows that nanoclusters of integrins organize phosphorylated FAK nanoclusters in focal adhesions, which are required for mechanosignalling and disassemble in response to inactivation signals.

bioRxiv · Feb 25, 2024 · PreprintCell Biology

Intrinsic self-organization of integrin nanoclusters within focal adhesions is required for cellular mechanotransduction

K. Jain, K. Y. E. Lim, M. P. Sheetz, P. Kanchanawong, R. Changede

The paper shows that integrin nanoclusters self-organize within focal adhesions at an optimal distance to enable mechanotransduction, with cytoplasmic factors like talin and FHOD1 playing key roles.

bioRxiv · Nov 20, 2023 · PreprintCell Biology

Coordination of focal adhesion nanostructure and mechano-signaling drives cardiomyocyte differentiation

J. Xiao, X. Zhong, J. W. Ang, D. C. P. Wong, C. J. M. Lee, R. S.-Y. Foo, P. Kanchanawong, B. C. Low

This study identifies BNIP-2 as a key organizer of focal adhesion nanostructure that enhances signaling and traction force, essential for cardiomyocyte differentiation.

bioRxiv · Nov 13, 2023 · PreprintCell Biology

Ground-state pluripotent stem cells are characterized by Rac1-dependent Cadherin-enriched F-actin protrusions

S. Liu, Y. Meng, P. Kanchanawong

This study identifies cadheropodia, Rac1-dependent actin structures in ground-state mESCs, which may serve as markers for pluripotency.

bioRxiv · Jun 15, 2023 · PreprintCell Biology

Focal adhesions are controlled by microtubules through local contractility regulation

J. Aureille, S. Barnett, I. Arnal, L. Lafanechere, B. C. Low, P. Kanchanawong, A. Mogilner, A. Bershadsky

This study shows microtubules control focal adhesion disassembly via KANK1-mediated local contractility regulation involving RhoA/ROCK and other proteins.

bioRxiv · Apr 17, 2023Cell Biology

Actin polymerization and crosslinking drive left-right asymmetry in single cell and cell collectives

Y. H. Tee, W. J. Goh, X. Yong, H. T. Ong, J. Hu, I. Y. Y. Tay, S. Shi, S. Jalal, S. F. H. Barnett, P. Kanchanawong, W. Huang, J. Yan, V. Thiagarajan, A. D. Bershadsky

The paper identifies actin polymerization regulators that drive chiral actin swirling and left-right asymmetry in single cells and cell collectives.

bioRxiv · Apr 22, 2021 · PreprintCell Biology

Enhancement of endothelialization by topographical features is mediated by PTP1B-dependent endothelial adherens junctions remodeling

A. Gorji, P. J. Y. Toh, Y.-C. Toh, Y. Toyama, P. Kanchanawong

This study shows that PTP1B inhibition combined with grating topography enhances endothelialization by remodeling endothelial adherens junctions and improving cell migration and proliferation.

bioRxiv · Sep 16, 2019Cell Biology

Mechanical Roles of Vinculin/β-catenin interaction in Adherens Junction

C. BERTOCCHI, A. Ravasio, H. T. Ong, Y. Toyama, P. Kanchanawong

The paper investigates the mechanical role of vinculin/β-catenin interaction in adherens junctions, showing that vinculin forms a direct structural connection with β-catenin to support mechanical tension and stabilize complexes.

bioRxiv · Sep 16, 2019Cell Biology

Molecular organization of integrin-based adhesion complexes in mouse Embryonic Stem Cells

S. Xia, E. K. F. Yim, P. Kanchanawong

This study investigates the molecular and structural organization of focal adhesions in mouse embryonic stem cells, revealing a compact nanoscale architecture and ECM-dependent regulation.

bioRxiv · Sep 13, 2018Cell Biology