Author

P. L. Nicolson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Pathology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

S. G. Thomas· 2 shared S. P. Watson· 2 shared A. Brill· 1 shared A. L. Dalby· 1 shared A. Maclachlan· 1 shared A. O. Khan· 1 shared A. Slater· 1 shared B. Grygielska· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

S. G. Thomas

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Author profile →

3 papers

Recent·Most cited

Spleen tyrosine kinase inhibition mitigates hemin-induced thromboinflammation in the lung and kidney of sickle cell mice

J. El-Awaisi, G. Perrella, N. Mayor, V. Tinkova, S. J. Cleary, B. Grygielska, S. P. Watson, J. D. Dimitrov, A. Brill, P. L. Nicolson, D. Kavanagh, N. Kalia, J. Rayes

This study shows that Syk inhibition reduces hemin-induced thromboinflammation and improves perfusion in the lungs and kidneys of sickle cell mice.

bioRxiv · May 4, 2024 · PreprintPathology

Analysis of Preplatelets and Their Barbell Platelet Derivatives by Imaging Flow Cytometry

S. Kemble, A. L. Dalby, G. C. Lowe, P. L. Nicolson, S. P. Watson, Y. A. Senis, S. G. Thomas, P. Harrison

This study uses imaging flow cytometry and microscopy to show that preplatelets and barbell platelets are immature structures that transform into mature platelets in mice and humans.

bioRxiv · Jul 30, 2021Cell Biology

Post-translational polymodification of β1 tubulin regulates motor protein localisation in platelet production and function

A. O. Khan, A. Slater, A. Maclachlan, P. L. Nicolson, J. A. Pike, J. S. S. Reyat, J. Yule, R. Stapley, S. G. Thomas, N. V. Morgan

The paper investigates how post-translational polymodifications of β1 tubulin regulate motor protein localization in platelet production and function using patient data, iPSC-derived megakaryocytes, and platelets.

Haematologica · Dec 17, 2020Peer-reviewedCell Biology

P. L. Nicolson · henhao