Author

P. Olofsson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 2 Cell Biology· 1 Ecology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:ecology & biodiversity· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. Dahlgren· 2 shared H. Forsman· 2 shared R. B. R. Azevedo· 2 shared R. Holmdahl· 2 shared S. Lind· 2 shared A. Brenninkmeijer· 1 shared A. Chabrolle· 1 shared A. Tynan· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

C. Dahlgren

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Mutational meltdown in asexual populations doomed to extinction

P. Olofsson, L. Chipkin, R. C. Daileda, R. B. R. Azevedo

The paper models mutational meltdown in asexual populations, showing they are doomed to extinction due to mutation accumulation and population decline.

bioRxiv · Jul 5, 2023Evolutionary Biology

Highly pathogenic avian influenza causes mass mortality in Sandwich tern (Thalasseus sandvicensis) breeding colonies across northwestern Europe

U. Knief, T. Bregnballe, I. Alfarwi, M. Ballmann, A. Brenninkmeijer, S. Bzoma, A. Chabrolle, J. Dimmlich, E. Engel, R. Fijn, K. Fischer, B. Haelterlein, M. Haupt, C. Herrmann, R. in 't Veld, , Ve

This study reports mass mortality of Sandwich terns due to HPAI A(H5N1) in northwestern Europe, with over 17% of the breeding population dying and high chick mortality observed.

bioRxiv · May 12, 2023 · PreprintEcology

A Branching Process Model of Evolutionary Rescue

R. B. R. Azevedo, P. Olofsson

The paper develops a branching process model to study evolutionary rescue, deriving probabilities and dynamics of population recovery through beneficial mutations.

bioRxiv · Jun 4, 2021Evolutionary Biology

Functional selective FPR1 signaling in favor of an activation of the neutrophil superoxide generating NOX2-complex

S. Lind, R. Holmdahl, P. Olofsson, C. Dahlgren, H. Forsman

This study identifies a novel FPR1 agonist, RE, that shows biased signaling and functional selectivity in human neutrophils, potentially useful for anti-inflammatory therapeutics.

bioRxiv · May 20, 2020Cell Biology

Antibody responses to immunization require sensory neurons

A. Tynan, T. Tsaava, M. Gunasekaran, I. Snee, T. Mak, P. Olofsson, U. Andersson, S. S. Chavan, K. J. Tracey

This study shows that TRPV1-expressing sensory neurons are required for antibody responses to novel antigens and that stimulating these neurons enhances antibody production.

bioRxiv · Nov 30, 2019 · PreprintImmunology

Functional and signaling characterization of the neutrophil FPR2 selective agonist Act-389949

S. Lind, M. Sundqvist, R. Holmdahl, C. Dahlgren, H. Forsman, P. Olofsson

This study characterizes Act-389949, a FPR2 agonist, showing it induces neutrophil signaling and chemotaxis comparable to WKYMVM, with increased stability against oxidation.

bioRxiv · Mar 8, 2019Pharmacology & Toxicology