Author

P.-Y. Tsai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

A. Adler· 1 shared A. J. Shumway· 1 shared A. R. Farghli· 1 shared B. Shui· 1 shared C. A. Lewis· 1 shared C. B. Clish· 1 shared C. Cheng· 1 shared C. Wong· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 8 mutual co-author links

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1 shared paperCancer Biology

A. Adler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma

R. K. Ma, P.-Y. Tsai, A. R. Farghli, A. J. Shumway, M. Kanke, J. D. Gordan, T. Gujral, K. Vakili, M. Nukaya, L. Noetzli, S. Ronnekleiv-Kelly, W. Broom, J. Barrow, P. Sethupathy

This paper identifies LINC00473 as a downstream mediator of DNAJB1-PRKACA fusion in fibrolamellar carcinoma, showing it promotes tumor growth and alters mitochondrial function.

bioRxiv · Jun 2, 2023Cancer Biology

ADO-MEDIATED SYNTHESIS OF TAURINE ALTERS THE CHROMATIN LANDSCAPE OF INGUINAL ADIPOSE TISSUE TO ENHANCE NON-SHIVERING THERMOGENESIS

P.-Y. Tsai, B. Shui, S. Lee, Y. Liu, Y. Qu, C. Cheng, K. Edwards, C. Wong, R. Meng-Killeen, P. Soloway, J. J. Barrow

This study shows taurine biosynthesis via ADO enhances NST in inguinal adipose tissue by remodeling chromatin to increase gene transcription for thermogenesis.

bioRxiv · Feb 2, 2023 · PreprintCell Biology

Equilibrative Nucleoside Transporter 3 is an IFN-stimulated Gene that Facilitates Viral Genome Release

Y.-T. Hsieh, T.-L. Tsai, C.-C. Tu, S.-Y. Huang, J.-W. Heng, P.-Y. Tsai, T.-L. Chao, Y.-M. Tsai, P.-C. Chang, C.-K. Lee, G.-Y. Yu, S.-Y. Chang, I. Dzhagalov, C.-L. Hsu

This study identifies ENT3 as an IFN-stimulated gene that supports viral genome release, showing its role in viral entry and replication.

bioRxiv · Apr 27, 2022 · PreprintImmunology

Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1

P.-Y. Tsai, M.-S. Lee, U. Jadhav, I. Naqvi, S. Madha, A. Adler, M. Mistry, S. Naumenko, C. A. Lewis, D. S. Hitchcock, F. R. Roberts, P. DelNero, T. Hank, K. C. Honselmann, V. Morales Oyarvide, , N. Y. Kalaany

This study shows that pancreatic cancer cells can adapt to nutrient deprivation by stabilizing glutamine synthetase via mTORC1, and this adaptation is reversible.

bioRxiv · Feb 16, 2020Cancer Biology