Author

S.-Y. Huang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Microbiology· 3 Bioengineering· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Organism:Drosophila· 2 Research Focus:host-pathogen & immune response· 2 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1

Frequent Co-Authors

H. Tao· 2 shared Y. Pommier· 2 shared Y. Sun· 2 shared A. Yang· 1 shared A.-S. Chiang· 1 shared C. S. Wong· 1 shared C.-C. Chan· 1 shared C.-C. Huang· 1 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 6 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

H. Tao

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

A cyclic dipeptide for salinity stress alleviation and the trophic flexibility of an endophyte reveal niches in salt marsh plant-microbe interactions

S.-H. W. Hung, P.-H. Yeh, T.-C. Huang, S.-Y. Huang, I.-C. Wu, C.-H. Liu, Y.-H. Lin, P.-R. Chien, F.-C. Huang, Y.-N. Ho, C.-H. Kuo, H.-H. Hwang, E.-P. I. Chiang, C.-C. Huang

This study identifies a cyclic dipeptide from an endophytic bacterium that alleviates salinity stress in plants, revealing insights into plant-microbe interactions in salt marshes.

ISME Communications · Mar 26, 2024Peer-reviewedMicrobiology

FOXO-regulated Deaf1 controls muscle regeneration through autophagy

K. Y. Goh, W. X. Lee, S. M. Choy, G. Krishnan Priyadarshini, K. Chua, Q. H. Tan, S. Y. Low, H. S. Chin, C. S. Wong, S.-Y. Huang, N. Y. Fu, J. Nishiyama, N. Harmston, H.-W. Tang

This study identifies Deaf1 as a FOXO-regulated factor that controls muscle regeneration via autophagy, showing its critical role in muscle stem cell survival and regeneration.

bioRxiv · Jan 12, 2024Cell Biology

Manipulation of Bacterial ROS Production Leads to Self-escalating DNA Damage and Resistance-resistant Lethality for Intracellular Mycobacteria

J. Song, M. Wang, H. Tao, A. Yang, Z. Zhu, S. Bai, M. Luo, J. Xu, X. Liu, Y. Sun, P. Hu, W.-L. Wong, F. Li, Y. Chen, Q. Cai, , X. Feng

This study develops a resistance-resistant antimicrobial by inducing catastrophic DNA damage in intracellular mycobacteria through a hybrid organoruthenium-natural product that manipulates bacterial ROS production.

bioRxiv · Jul 7, 2023 · PreprintMicrobiology

Virulence, Aggressiveness, and Fungicide Sensitivity of Phytophthora spp. Associated with Soybean in Illinois

D. Cerritos-Garcia, S.-Y. Huang, N. M. Kleczewski, S. Mideros

The paper characterizes virulence, aggressiveness, and fungicide sensitivity of Phytophthora species causing soybean root rot in Illinois.

bioRxiv · Jun 30, 2022Plant Biology

Equilibrative Nucleoside Transporter 3 is an IFN-stimulated Gene that Facilitates Viral Genome Release

Y.-T. Hsieh, T.-L. Tsai, C.-C. Tu, S.-Y. Huang, J.-W. Heng, P.-Y. Tsai, T.-L. Chao, Y.-M. Tsai, P.-C. Chang, C.-K. Lee, G.-Y. Yu, S.-Y. Chang, I. Dzhagalov, C.-L. Hsu

This study identifies ENT3 as an IFN-stimulated gene that supports viral genome release, showing its role in viral entry and replication.

bioRxiv · Apr 27, 2022 · PreprintImmunology

Dihydroceramide desaturase promotes the formation of intraluminal vesicles and inhibits autophagy to increase exosome production

C.-Y. Wu, J.-G. Jhang, W.-S. Lin, C.-W. Lin, L.-A. Chu, A.-S. Chiang, H.-C. Ho, C.-C. Chan, S.-Y. Huang

This study shows that DEGS1/Ifc promotes exosome production by enhancing intraluminal vesicle formation and inhibiting autophagic degradation of multivesicular endosomes in Drosophila.

bioRxiv · Nov 10, 2020Cell Biology

A polymer gel index-matched to water enables diverse applications in fluorescence microscopy

X. Han, Y. Su, H. White, K. M. O'Neill, N. Y. Morgan, R. Christensen, D. Potarazu, H. D. Vishwasrao, S. Xu, Y. Sun, S.-y. Huang, M. W. Moyle, Q. Dai, Y. Pommier, E. Giniger, , H. Shroff

This paper introduces a polymer gel matched to water's refractive index, enabling high-resolution imaging of living cells and organisms in thick layers.

bioRxiv · Oct 4, 2020Bioengineering

Topoisomerase 3B (TOP3B) DNA and RNA Cleavage Complexes and Pathway to Repair TOP3B-linked RNA and DNA Breaks

S. Saha, S.-Y. Huang, U. Jo, H. Zhang, Y.-C. Tse-Dinh, Y. Pommier

The paper identifies a pathway for repairing TOP3B DNA and RNA cleavage complexes, showing that TDP2 excises ubiquitinated TOP3Bccs after proteasomal degradation.

bioRxiv · Mar 22, 2020Cell Biology

Molecular mechanism of evolution and human infection with the novel coronavirus (2019-nCoV)

J. He, H. Tao, Y. Yan, S.-Y. Huang, Y. Xiao

This study investigates the molecular mechanisms of 2019-nCoV binding to human ACE2 and its evolutionary advantages over SARS-CoV using computational methods.

bioRxiv · Feb 17, 2020Microbiology