Author

Y.-M. Tsai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

S.-Y. Chang· 4 shared T.-L. Chao· 4 shared H.-C. Kao· 3 shared C. Ma· 1 shared C.-C. Tu· 1 shared C.-H. Lin· 1 shared C.-H. Wong· 1 shared C.-K. Lee· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersMicrobiology

S.-Y. Chang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Equilibrative Nucleoside Transporter 3 is an IFN-stimulated Gene that Facilitates Viral Genome Release

Y.-T. Hsieh, T.-L. Tsai, C.-C. Tu, S.-Y. Huang, J.-W. Heng, P.-Y. Tsai, T.-L. Chao, Y.-M. Tsai, P.-C. Chang, C.-K. Lee, G.-Y. Yu, S.-Y. Chang, I. Dzhagalov, C.-L. Hsu

This study identifies ENT3 as an IFN-stimulated gene that supports viral genome release, showing its role in viral entry and replication.

bioRxiv · Apr 27, 2022 · PreprintImmunology

Impact of glycosylation on a broad-spectrum vaccine against SARS-CoV-2

H.-Y. Huang, H.-Y. Liao, X. Chen, S.-W. Wang, C.-W. Cheng, M. Shahed-Al-Mahmud, T.-H. Chen, J. M. Lo, Y.-M. Liu, Y.-M. Wu, H.-H. Ma, Y.-H. Chang, H.-Y. Tsai, Y.-C. Chou, Y.-P. Hsueh, , C.-H. Wong

This study shows that trimming N-glycans from the SARS-CoV-2 spike protein enhances immune responses and protection against variants in hACE2 mice.

bioRxiv · May 25, 2021 · PreprintMicrobiology

D614G Substitution of SARS-CoV-2 Spike Protein Increases Syncytium Formation and Viral Transmission via Enhanced Furin-mediated Spike Cleavage

Y.-W. Cheng, T.-L. Chao, C.-L. Li, S.-H. Wang, H.-C. Kao, Y.-M. Tsai, H.-Y. Wang, C.-L. Hsieh, P.-J. Chen, S.-Y. Chang, S.-H. Yeh

This study shows the D614G substitution in SARS-CoV-2 spike protein increases viral transmission by enhancing furin-mediated cleavage, leading to more syncytium formation and higher virus titers.

bioRxiv · Jan 27, 2021Microbiology

Distinct Inductions of and Responses to Type I and Type III Interferons PromoteInfections in Two SARS-CoV-2 Isolates

F. Hsin, T.-L. Chao, Y.-R. Chan, H.-C. Kao, W.-D. Liu, J.-T. Wang, Y.-H. Pang, C.-H. Lin, Y.-M. Tsai, J.-Y. Lin, S.-Y. Chang, H. M. Liu

This study compares two SARS-CoV-2 isolates and finds they induce weak antiviral responses and are less neutralized by antibodies.

bioRxiv · Apr 30, 2020 · PreprintMicrobiology