Author

Pascal Lexmond

Erasmus MC

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Organism:virus· 1

Frequent Co-Authors

Mark Pronk· 3 shared Ron A. M. FouchieriD· 3 shared Adam MeijeriD· 2 shared Björn F. KoeliD· 2 shared Geert‐Jan BoonsiD· 2 shared Robert P. de VriesiD· 2 shared Ruonan Liang· 2 shared Sarah L. JamesiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

Mark Pronk

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Loss of hemagglutination ability by H3N2 influenza A virus, subclade K.

Ruonan Liang, Pascal Lexmond, Oliver C. Grant, Mark Pronk, Roland J. Pieters, Ron A. M. Fouchier, Geert‐Jan Boons, Björn F. Koel, Robert P. de Vries

This study investigates how amino acid substitutions in H3N2 influenza A virus subclade K affect hemagglutination and glycan binding, showing a preference for elongated glycans not present on turkey erythrocytes.

bioRxiv · Jul 20, 2026 · PreprintMicrobiology

Emergence and antigenic characterisation of influenza A(H3N2) viruses with hemagglutinin substitutions N158K and K189R during the 2024/25 influenza season

Björn F. Koel, Alexander Byrne, Samuel A. Turner, Sarah L. James, Ruth Harvey, Mónica Galiano, Christine Carr, Pascal Lexmond, Mark Pronk, Ruonan Liang, Geert‐Jan Boons, Robert P. de Vries, Dirk Eggink, Nicola S. Lewis, Derek Smith, , Ron A. M. Fouchier

This study characterizes the emergence and antigenic properties of influenza A(H3N2) viruses with N158K and K189R substitutions, showing they are antigenically distinct from vaccine strains and may reduce vaccine effectiveness.

bioRxiv · Feb 10, 2026 · PreprintMicrobiology

A vaccine antigen central in influenza A(H5) virus antigenic space confers subtype-wide immunity

Adinda Kok, Samuel H. Wilks, Sina Türeli, Sarah L. James, Theo M. Bestebroer, David F. Burke, Mathis Funk, Stefan van der Vliet, Monique I. J. Spronken, Willemijn F. Rijnink, David J. Pattinson, Dennis de Meulder, Miruna E. Rosu, Pascal Lexmond, Judith M. A. van den Brand, , Mathilde Richard

The paper creates a high-resolution antigenic map of A(H5) HA and uses it to design vaccine antigens that confer broad immunity against diverse A(H5) viruses.

Nature · Oct 15, 2025Peer-reviewedMicrobiology

Rapid SARS-CoV-2 whole genome sequencing for informed public health decision making in the Netherlands

Bas B. Oude Munnink, David F. Nieuwenhuijse, Mart L. Stein, Aine Niamh O’Toole, Manon R. Haverkate, Madelief Mollers, Sandra Kengne Kamga, Claudia M. E. Schapendonk, Mark Pronk, Pascal Lexmond, Anne van der Linden, Theo M. Bestebroer, Irina Chestakova, Ronald J. Overmars, Stefan van Nieuwkoop, , on behalf of the Dutch-Covid-19 response team

The paper describes the early response to the SARS-CoV-2 outbreak in the Netherlands, focusing on whole genome sequencing and its role in public health decision making.

bioRxiv · Apr 21, 2020 · PreprintGenomics