Author

Paul Aisen

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:imaging· 3 Research Focus:spatial domain detection· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Andrew J. SaykiniD· 3 shared Alzheimer’s Disease Neuroimaging Initiative· 2 shared Arthur W. TogaiD· 2 shared Bret Borowski· 2 shared Chad Ward· 2 shared Charles S DeCarliiD· 2 shared Chester A. MathisiD· 2 shared Clifford R. JackiD· 2 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Andrew J. SaykinORCID

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Author profile →

3 papers

Recent·Most cited

Continuous amyloid staging complements global amyloid burden in early Alzheimer's disease

Haoyuan Liu, Mingzhao Tong, Shiaofen Fang, Elizabeth C. Mormino, Reisa Anne Sperling, Paul Aisen, Rachel F. Buckley, Paul Crane, Timothy J. Hohman, Andrew J. Saykin, Jingwen Yan, For the Alzheimers Disease Neuroimaging Initiative

This paper develops a continuous amyloid staging score from regional amyloid PET to improve early Alzheimer's disease staging and cognitive risk stratification.

bioRxiv · Oct 11, 2026 · PreprintNeuroscience

Spread of pathological tau proteins through communicating neurons in human Alzheimer’s disease

Jacob W. Vogel, Yasser Iturria‐Medina, Olof T. Strandberg, Ruben A Smith, Elizabeth Levitis, Alan Charles Evans, Oskar Hansson, Alzheimer’s Disease Neuroimaging Initiative, Michael Walter Weiner, Paul Aisen, Ronald Carl Petersen, Clifford R. Jack, William J. Jagust, John Q. Trojanowki, Arthur W. Toga, , Mark A. Mintun

This study uses an epidemic spreading model to show that tau spreads through neuronal connections in Alzheimer's disease, with beta-amyloid accelerating this process in some brain regions.

Nature Communications · May 26, 2020Peer-reviewedNeuroscience

Heritability of regional brain volumes in large-scale neuroimaging and genetic studies

Bingxin Zhao, Joseph G. Ibrahim, Yun Li, Tengfei Li, Yue Wang, Yue Shan, Ziliang Zhu, Fan Zhou, Jingwen Zhang, Chao Huang, Huiling Liao, Liuqing Yang, Paul M. Thompson, Hongtu Zhu B, Pediatric Imaging, Neurocognition and Genetics (PING), , John Hsiao

The paper examines the heritability of regional brain volumes using genetic and neuroimaging data from multiple cohorts, finding high heritability and consistent patterns across populations.

Cerebral Cortex · Jul 2, 2018Peer-reviewedGenetics