Author

Paula Dobrinić

University of Oxford

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1

Frequent Co-Authors

Robert J. KloseiD· 3 shared Aleksander SzczurekiD· 2 shared Miles K. HuseyiniD· 2 shared Nadezda A. FursovaiD· 2 shared Neil P. BlackledgeiD· 2 shared Angelika FeldmanniD· 1 shared Anna Lastuvkova· 1 shared Anne H. TurberfieldiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Robert J. KloseORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency

Paula Dobrinić, Aleksander Szczurek, Robert J. Klose

This study identifies PRC1's role in Polycomb-mediated gene repression by showing it independently counteracts RNA polymerase II binding and controls transcriptional burst frequency.

Nature Structural & Molecular Biology · Oct 1, 2021Peer-reviewedMolecular Biology

BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome

Nadezda A. Fursova, Anne H. Turberfield, Neil P. Blackledge, Emma L. Findlater, Anna Lastuvkova, Miles K. Huseyin, Paula Dobrinić, Robert J. Klose

The paper shows that BAP1 limits H2AK119ub1 levels, which affects gene expression and Polycomb complex function, revealing a general mechanism for controlling transcriptional potential.

bioRxiv · Nov 13, 2020Molecular Biology

Cohesin disrupts polycomb-dependent chromosome interactions

JDP Rhodes, Angelika Feldmann, Benjamín Hernández-Rodríguez, Noèlia Díaz, JM Brown, Nadezda A. Fursova, Neil P. Blackledge, Praveen Prathapan, Paula Dobrinić, Miles K. Huseyin, Aleksander Szczurek, Kai Kruse, KA Nasmyth, VJ Buckle, Juan M. Vaquerizas, Robert J. Klose

The paper shows cohesin disrupts polycomb-dependent chromosomal interactions to regulate gene repression in embryonic stem cells.

bioRxiv · Mar 30, 2019 · PreprintGenetics