Author

Pranathi Meda Krishnamurthy

University of Massachusetts Chan Medical School

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1 Organism:zebrafish· 1

Frequent Co-Authors

Jonathan K. WattsiD· 2 shared Aamir MiriD· 1 shared Ahmet Rasit OzturkiD· 1 shared Alireza EdrakiiD· 1 shared Craig C. MelloiD· 1 shared Erik J. SontheimeriD· 1 shared Feston IdriziiD· 1 shared Gitali DeviiD· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMolecular Biology

Jonathan K. WattsORCID

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2 papers

Recent·Most cited

Quantification of Antisense Oligonucleotides by Splint Ligation and Quantitative Polymerase Chain Reaction

Minwook Shin, Pranathi Meda Krishnamurthy, Gitali Devi, Jonathan K. Watts

This paper describes a method to detect and quantify antisense oligonucleotides in biological samples using splint ligation and quantitative PCR, showing sensitivity across multiple tissues and ASO types.

Nucleic Acid Therapeutics · Dec 20, 2021Peer-reviewedMolecular Biology

5' Modifications Improve Potency and Efficacy of DNA Donors for Precision Genome Editing

Krishna Sumanth Ghanta, Zexiang Chen, Aamir Mir, Gregoriy A. Dokshin, Pranathi Meda Krishnamurthy, Yeonsoo Yoon, Judith Gallant, Ping Xu, Xiao-Ou Zhang, Ahmet Rasit Ozturk, Masahiro Shin, Feston Idrizi, Pengpeng Liu, Hassan Gneid, Alireza Edraki, , Craig C. Mello

This study shows that 5' modifications to DNA repair templates enhance precision genome editing efficiency in multiple animal models and human cells.

eLife · Oct 19, 2021Peer-reviewedMolecular Biology