Author

Q. R. Lu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:mechanistic / dynamical model· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

A. Bikfalvi· 1 shared A. Eichmann· 1 shared A. G. Jegga· 1 shared A. Idbaih· 1 shared A. Kuenzi· 1 shared B. Tavitian· 1 shared C. Knosp· 1 shared C. Lesaffre· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. Bikfalvi

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Targeting of Cdc42 GTPase in regulatory T cells unleashes anti-tumor T cell immunity

K. W. Kalim, J.-Q. Yang, M. Wunderlich, V. Modur, P. Nguyen, Y. Li, T. Wen, A. Kuenzi, R. Verma, Q. R. Lu, A. G. Jegga, Y. Zheng, F. Guo

This study shows that targeting Cdc42 in regulatory T cells promotes anti-tumor immunity without causing autoimmunity by inducing Treg plasticity and altering pH through carbonic anhydrase I.

bioRxiv · Sep 23, 2021 · PreprintImmunology

SLIT2-ROBO signaling in tumor-associated microglia/macrophages drives glioblastoma immunosuppression and vascular dysmorphia

L. H. Geraldo, Y. Xu, L. Jacob, L. Pibouin-Fragner, R. Rao, N. Maissa, M. Verreault, N. Lemaire, C. Knosp, C. Lesaffre, T. Daubon, J. Dejaegher, L. Solie, J. Rudewicz, T. Viel, , T. Mathivet

This study shows that SLIT2-ROBO signaling in tumor-associated microglia/macrophages promotes glioblastoma immunosuppression and vascular dysmorphia, and its inhibition reduces tumor growth and enhances therapy.

bioRxiv · Apr 12, 2021Cancer Biology