Author

Yong-Hong Yan

National Institute of Biological Sciences, Beijing

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Meng‐Qiu DongiD· 3 shared Ao GuoiD· 1 shared Chengming ZhuiD· 1 shared Demin Xu· 1 shared Fang BaiiD· 1 shared Haochen Lyu· 1 shared Ke WangiD· 1 shared Qiang Fan· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

Meng‐Qiu DongORCID

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3 papers

Recent·Most cited

Selective activation of IRE-1 safeguards restoration of translation and organismal rejuvenation from adult reproductive diapause

Qiang Fan, Ao Guo, 王淑娟, Wuling Yang, Yong-Hong Yan, Meng‐Qiu Dong

This study shows that refeeding reverses aging-like phenotypes in C. elegans reproductive diapause by selectively activating the IRE-1 branch of UPRER and enhancing protein synthesis and folding.

bioRxiv · Mar 20, 2026 · PreprintCell Biology

Dual Inhibition of MYRF Cleavage by Its JM Region and PAN-1 CCT Gates Developmental Timing in C. elegans

Zhimin Xu, Xiaoting Feng, Haochen Lyu, Yong-Hong Yan, Yongqi Zhou, Zhizhi Wang, Fang Bai, Meng‐Qiu Dong, Yingchuan Billy Qi

The paper identifies two inhibitory mechanisms regulating MYRF-1 cleavage in C. elegans, showing their role in controlling developmental timing.

bioRxiv · Jan 9, 2026 · PreprintDevelopmental Biology

Compartmentalized localization of perinuclear proteins within germ granules in C. elegans

Xiaona Huang, Xuezhu Feng, Yong-hong Yan, Demin Xu, Ke Wang, Chengming Zhu, Meng‐Qiu Dong, Shouhong Guang, Xiangyang Chen

The paper identifies subcompartments within C. elegans germ granules and maps perinuclear proteins to specific regions, revealing a novel D granule and the role of MIP-1/EDDG-1 in germ granule architecture.

Developmental Cell · Dec 31, 2024Peer-reviewedCell Biology