Author

R. Gassmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 8

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Research Focus:cell signaling & trafficking· 8 Organism:C. elegans· 7 Approach:experimental assay· 7 Research Focus:development & morphogenesis· 6 Research Focus:chromatin & epigenetic regulation· 2 Assay:imaging· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. X. Carvalho· 4 shared D. J. Barbosa· 3 shared A. R. G. De-Castro· 2 shared A. Xavier de Carvalho· 2 shared C. M. C. Abreu· 2 shared D. K. Cheerambathur· 2 shared D. R. M. Rodrigues· 2 shared J. B. Gama· 2 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersCell Biology

A. X. Carvalho

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Author profile →

8 papers

Recent·Most cited

Dynein directs prophase centrosome migration to control the stem cell division axis in the developing C. elegans epidermis

C. Carvalho, D. J. Barbosa, R. Celestino, E. Zanin, A. X. Carvalho, R. Gassmann

This study shows dynein orients spindle migration in C. elegans epidermal stem cells, ensuring proper asymmetric division and tissue organization.

bioRxiv · Sep 25, 2023 · PreprintCell Biology

Hot-wiring dynein-2 uncovers roles for IFT-A in retrograde train assembly and motility

F. Goncalves-Santos, A. R. G. De-Castro, D. R. M. Rodrigues, M. J. G. De-Castro, R. Gassmann, C. M. C. Abreu, T. J. Dantas

This study uses CRISPR/Cas9 to disable dynein-2 autoinhibition in C. elegans, revealing IFT-A's roles in retrograde IFT train assembly and motility.

bioRxiv · May 10, 2023 · PreprintCell Biology

Nuclear-enriched protein phosphatase 4 ensures outer kinetochore assemblyprior to nuclear dissolution

H. Rocha, P. A. Simoes, J. Budrewicz, P. Lara-Gonzalez, A. Xavier de Carvalho, J. Dumont, A. Desai, R. Gassmann

The paper shows that PP4 ensures outer kinetochore assembly before nuclear envelope breakdown, which is critical for proper chromosome segregation.

bioRxiv · Sep 1, 2022Cell Biology

JIP3 regulates bi-directional organelle transport in neurons through its interaction with dynein and kinesin-1

R. Celestino, J. B. Gama, A. F. Castro-Rodrigues, D. J. Barbosa, E. A. d'Amico, A. Musacchio, A. Xavier de Carvalho, J. H. Morais-Cabral, R. Gassmann

This study shows JIP3 interacts with dynein and kinesin-1 to regulate bi-directional organelle transport in neurons, preventing lysosome accumulation.

bioRxiv · Oct 11, 2021Cell Biology

WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing

A. R. G. De-Castro, D. R. M. Rodrigues, M. J. G. De-Castro, N. Vieira, C. Vieira, A. X. Carvalho, R. Gassmann, C. M. C. Abreu, T. J. Dantas

This study identifies WDR-60's role in dynein-2 loading into cilia, showing it is essential for retrograde IFT and transition zone crossing.

bioRxiv · Sep 19, 2021Cell Biology

Dynein-dynactin segregate meiotic chromosomes in C. elegans spermatocytes

D. Barbosa, V. Teixeira, J. Duro, A. Carvalho, R. Gassmann

This study shows that dynein-dynactin are essential for meiotic chromosome segregation in C. elegans spermatocytes, with a mutation causing aneuploidy and developmental defects.

bioRxiv · Oct 19, 2020Cell Biology

Self-assembly of the RZZ complex into filaments drives kinetochore expansion in the absence of microtubule attachment

R. Gassmann, C. Pereira, R. M. Reis, J. B. Gama, D. K. Cheerambathur, A. X. Carvalho

This study shows that the RZZ complex self-assembles into filaments to drive kinetochore expansion when microtubules are not attached, facilitating SAC signaling and chromosome segregation.

bioRxiv · Mar 15, 2018Cell Biology

Dynactin Binding To Tyrosinated Microtubules Promotes Centrosome Centration In C. Elegans By Enhancing Dynein-Mediated Organelle Transport

D. J. Barbosa, J. Duro, D. K. Cheerambathur, B. Prevo, A. X. Carvalho, R. Gassmann

This study shows that dynactin's binding to tyrosinated microtubules enhances dynein-mediated organelle transport, which is critical for centrosome centration in C. elegans zygotes.

bioRxiv · Apr 24, 2017Cell Biology