Author

R. H. Gilman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 5 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Sette· 3 shared C. S. Lindestam Arlehamn· 3 shared M. Saito· 3 shared A. D. DeSilva· 2 shared B. Gunasena· 2 shared B. Peters· 2 shared Chagas working group· 2 shared M. R. Mugnier· 2 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersImmunology

A. Sette

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Immunologic changes are detectable in the peripheral blood transcriptome of clinically asymptomatic Chagas cardiomyopathy patients

C. Duque, J. So, Y. E. Castro-Sesquen, K. DeToy, S. A. G. Guarnizo, F. Jahanbakhsh, E. M. Machaca, M. Miranda-Schaeubinger, I. Chakravarti, V. Cooper, M. E. Schmidt, A. Luigi, R. Marcus, K. R. Talaat, R. H. Gilman, , Chagas working group

This study identifies immune-related gene expression changes in asymptomatic Chagas cardiomyopathy patients, suggesting unique immune mechanisms in early disease progression.

bioRxiv · Oct 3, 2023Immunology

Identification of differentially recognized T cell epitopes in the spectrum of Mtb infection

S. Panda, J. Morgan, C. Cheng, M. Saito, R. H. Gilman, N. Ciobanu, V. Crudu, D. G. Catanzaro, A. Catanzaro, T. Rodwell, J. S. Perera, T. Chathuranga, B. Gunasena, A. D. DeSilva, B. Peters, , C. S. Lindestam Arlehamn

The paper identifies differentially recognized T cell epitopes in Mtb infection stages using a proteome-wide screen and Fluorospot assay, revealing epitopes specific to active TB and potential vaccine targets.

bioRxiv · Apr 12, 2023 · PreprintImmunology

Amplicon sequencing reveals complex infection in infants congenitally infected with Trypanosoma cruzi and informs the dynamics of parasite transmission

J. M. Hakim, A. Waltmann, F. Tinajeros, O. Kharabora, E. Malaga Machaca, M. Calderon, M. d. C. Menduina, J. Wang, D. Rueda, M. Zimic, M. Verastegui, J. J. Juliano, R. H. Gilman, M. R. Mugnier, N. M. Bowman, Chagas working group

The paper uses amplicon sequencing to analyze parasite strain diversity in mothers and infants infected with Trypanosoma cruzi, finding multiple strains in some individuals and increased diversity in infants post-birth.

bioRxiv · Nov 16, 2022Microbiology

Peripheral blood T-cell deficiency and hyperinflammatory monocyte responses associate with MAC lung disease

C. S. Lindestam Arlehamn, B. Benson, R. Kuan, K. A. Dill-McFarland, G. J. Peterson, S. Paul, F. K. Nguyen, R. H. Gilman, M. Saito, R. Taplitz, M. Arentz, C. H. Goss, M. L. Aitken, D. J. Horne, J. A. Shah, , T. R. Hawn

The paper investigates immune responses in individuals with MAC lung disease, finding reduced T-cell responses and hyperinflammatory monocyte activity.

bioRxiv · Mar 25, 2022 · PreprintImmunology

EXPRESSION OF Mycobacterium tuberculosis RpsA IN Mycobacterium smegmatis INCREASES SUSCEPTIBILITY TO PYRAZINAMIDE

R. A. Antiparra, M. Santos, A. K. Toledo, R. H. Gilman, D. E. Kirwan, P. Sheen, M. Zimic

This study shows that expressing Mycobacterium tuberculosis RpsA in Mycobacterium smegmatis reduces its susceptibility to pyrazinamide.

bioRxiv · Mar 31, 2020 · PreprintMicrobiology

The genetic structure and adaptation of Andean highlanders and Amazonian dwellers is influenced by the interplay between geography and culture

V. Borda, I. Alvim, M. M. Aquino, C. Silva, G. B. Soares-Souza, T. P. Leal, M. O. Scliar, R. Zamudio, C. Zolini, C. Padilla, O. Caceres, K. Levano, C. Sanchez, O. Trujillo, P. Flores-Villanueva, , H. Guio

This paper examines the genetic structure and adaptation of Andean highlanders and Amazonian dwellers, showing how geography and culture influence genetic differentiation and natural selection.

bioRxiv · Jan 30, 2020Evolutionary Biology

No cell is an island: circulating T cell:monocyte complexes are markers of immune perturbations

J. G. Burel, M. Pomaznoy, C. S. Lindestam Arlehamn, D. Weiskopf, R. da Silva Antunes, Y. Jung, V. Schulten, M. Babor, G. Seumois, J. A. Greenbaum, S. Premawansa, G. Premawansa, A. Wijewickrama, D. Vidanagama, B. Gunasena, , B. Peters

The paper identifies T cell:monocyte complexes in human blood as biological immune interactions, not technical artifacts, and shows their frequency changes with immune perturbations.

bioRxiv · Feb 21, 2019 · PreprintImmunology