The paper assembles and annotates haplotype-resolved genomes of grapevines to uncover genetic diversity and disease resistance mechanisms, identifying structural variants linked to downy mildew resistance.

bioRxiv · Feb 28, 2024 · PreprintPlant Biology

Armillaria korhonenii, the sixteenth biological species of Armillaria from China

J. Liu, G. Qin, J. Chen, J. Song, Z. Yan, S. Yang, M.-h. Tian, X. Xu, C. Zhang, T. Luangharn, C. S. Bhunjun, F. Yu, Z. Yang

The paper describes a new species of Armillaria, Armillaria korhonenii, based on phylogenetic, morphological, and mating test evidence, identifying it as the sixteenth biological species in China.

bioRxiv · Dec 4, 2023 · PreprintMicrobiology

Ras-mediated homeostatic control of front-back signaling dictates cell polarity

Y. Lin, D. S. Pal, P. Banerjee, T. Banerjee, G. Qin, Y. Deng, J. Borleis, P. A. Iglesias, P. Devreotes

This study uses optogenetics to show that RasGAPs regulate cell polarity by enhancing actomyosin contractility at the back and F-actin polymerization at the front.

bioRxiv · Aug 30, 2023Cell Biology

Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia

G. Qin, J. Dai, S. Chien, T. J. Martins, B. Loera, Q. Nguyen, M. L. Oakes, B. Tercan, B. Aguilar, L. Hagen, J. McCune, R. Gelinas, R. J. Monnat, I. Shmulevich, P. S. Becker

The paper identifies mutation patterns linked to drug sensitivity in AML using integrated computational and experimental analysis.

bioRxiv · May 24, 2023Cell Biology

ABLs and TMKs are co-receptors for extracellular auxin

Y. Yu, W. Tang, W. Lin, W. Li, X. Zhou, Y. Li, R. Chen, R. Zheng, G. Qin, W. Cao, P. Perez, R. Huang, J. Ma, J. Lin, L. Jiang, , Z. Yang

The paper identifies ABL1 and ABL2 as new auxin receptors that function with TMKs as co-receptors for extracellular auxin, overlapping with but distinct from ABP1.

bioRxiv · Nov 28, 2022Plant Biology

Subcellular Redox Responses Reveal Different Cu-dependent Antioxidant Defenses between Mitochondria and Cytosol

Y. Zhang, M.-H. Wen, G. Qin, C. Cai, T.-Y. Chen

This study investigates Cu-dependent antioxidant defenses in mitochondria and cytosol using redox sensors and proteomics, revealing distinct redox responses and protein changes in each compartment.

bioRxiv · Jul 21, 2022Biophysics

MicroRNA775 Promotes Intrinsic Leaf Size and Reduces Cell Wall Pectin Level via a Target Galactosyltransferase in Arabidopsis

L. Li, H. Zhang, Y. Zhuang, Z. Guo, Y. Suo, J. Du, Z. Gao, J. Pan, L. Li, T. Wang, L. Xiao, G. Qin, Y. Jiao, H. Cai

This study identifies miR775 as a regulator of leaf size in Arabidopsis by silencing GALT9, a galactosyltransferase that affects cell wall pectin levels and elasticity.

bioRxiv · Sep 17, 2020 · PreprintPlant Biology

Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories

Y. Su, D. Chen, C. Lausted, D. Yuan, J. Choi, C. Dai, V. Voillet, K. Scherler, P. Troisch, V. R. Duvvuri, P. Baloni, G. Qin, B. Smith, S. Kornilov, C. Rostomily, , the

This study integrates multi-omic data from COVID-19 patients to identify immune response patterns linked to disease severity.

bioRxiv · Jul 27, 2020 · PreprintImmunology

A novel protein complex that regulates active DNA demethylation in Arabidopsis

P. Liu, W.-F. Nie, X. Xiong, Y. Wang, Y. Jiang, P. Huang, X. Lin, G. Qin, H. Huang, Q. Niu, J. Du, Z. Lang, R. Lozano-Duran, J.-K. Zhu

This paper identifies a novel protein complex in Arabidopsis that regulates ROS1-mediated active DNA demethylation and targets ROS1 to specific genomic regions.

bioRxiv · Feb 21, 2020Plant Biology

Transcriptome analysis of the Larimichthys polyactis under heat and cold stress

T. Chu, F. Liu, G. Qin, W. Zhan, M. Wang, B. Lou

This study identifies differentially expressed genes and pathways in small yellow croaker liver under heat and cold stress, providing insights into temperature stress responses for aquaculture improvement.

bioRxiv · Sep 23, 2019Physiology