Author

R. M. Kaake

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

N. J. Krogan· 3 shared B. J. Polacco· 2 shared A. Gaba· 1 shared A. K. A. Sudarsan· 1 shared A. Sali· 1 shared A. Shayeganmehr· 1 shared C. Guo· 1 shared D. A. Agard· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

N. J. Krogan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Protein interaction map of APOBEC3 enzyme family reveals deamination-independent role in cellular function

G. M. Jang, A. K. A. Sudarsan, A. Shayeganmehr, E. P. Munhoz, R. Lao, A. Gaba, M. G. Rodriguez, R. P. Love, B. J. Polacco, Y. Zhou, N. J. Krogan, R. M. Kaake, L. Chelico

The paper identifies novel protein and RNA interactions of APOBEC3 enzymes, revealing deamination-independent roles in RNA biology and cancer.

bioRxiv · Feb 6, 2024Biochemistry

Structure and dynamics of the essential endogenous mycobacterial polyketide synthasePks13

S. K. Kim, M. S. Dickinson, J. S. Finer-Moore, Z. Guan, R. M. Kaake, I. Echeverria, J. Chen, E. H. Pulido, A. Sali, N. J. Krogan, O. S. Rosenberg, R. M. Stroud

This paper determines the structure and dynamics of the mycobacterial polyketide synthase Pks13 using cryoEM and complementary techniques, revealing intermediate states and substrate binding.

bioRxiv · Jan 27, 2023Biochemistry

De novo protein identification in mammalian sperm using high-resolution in situ cryo-electron tomography

Z. Chen, M. Shiozaki, K. M. Haas, S. Zhao, C. Guo, B. J. Polacco, Z. Yu, N. J. Krogan, R. M. Kaake, R. D. Vale, D. A. Agard

The paper identifies novel sperm proteins in mammals using cryo-electron tomography and AlphaFold2 models, revealing their structural roles in flagellar mechanics.

bioRxiv · Sep 28, 2022Biophysics