Author

R. Okamoto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:deep learning· 2 Organism:human· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. Koseki· 1 shared A. Kosugi· 1 shared A.-S. Kroell· 1 shared B. S. Coller· 1 shared B. Treutlein· 1 shared C. Locuson· 1 shared D. Nesic· 1 shared E. Ohshina· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperCell Biology

A. Koseki

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A high-fidelity in vitro model of the human intestinal epithelium

S. Fujii, S. T. Espenschied, V. Anand, J. Bettencourt-Silva, Y. Han, G. Ito, A. Koseki, A. Kosugi, J. Kozlowski, R. Matsumoto, S. Meng, N. Mulligan, R. J. Musich, K. Newhall, E. Ohshina, , T. S. Stappenbeck

This paper develops an in vitro model of the human intestinal epithelium that closely mimics in vivo cell types using single-cell transcriptomics and a biomedical foundation model.

bioRxiv · Jan 1, 2024 · PreprintCell Biology

Human neuron subtype programming through combinatorial patterning with scRNA-seq readouts

H.-C. Lin, J. Janssens, A.-S. Kroell, P. Hornauer, M. Santel, R. Okamoto, K. Karava, M. Priouret, M. P. Garcia, M. Schroeter, J. G. Camp, B. Treutlein

The paper programs human neuron subtypes using combinatorial patterning and scRNA-seq to identify diverse neuron types and their developmental signaling networks.

bioRxiv · Dec 12, 2023 · PreprintBioengineering

Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations

J. Li, Y. Fukase, Y. Shang, W. Zou, J. Munoz-Felix, L. Buitrago, J. van Agthoven, Y. Zhang, R. Hara, Y. Tanaka, R. Okamoto, T. Yasui, T. Nakahata, T. Imaeda, K. Aso, , B. S. Coller

This paper designs and evaluates two small-molecule Vβ3 antagonists that inhibit cell adhesion and bone resorption without inducing receptor conformational changes or enhancing angiogenesis at low concentrations.

bioRxiv · May 24, 2019Pharmacology & Toxicology